Olmesartan lactone impurity
Based on 1 Customer Validation
Olmesartan lactone impurity is an impurity of Olmesartan (HY-17004). Olmesartan is an angiotensin II receptor (AT1R) antagonist that is used in hypertension research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.27%
- CAS 番号: 849206-43-5
- 分子式: C24H24N6O2
- 分子量:428.49
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Olmesartan is an angiotensin II type 1 (AT1) receptor antagonist without PPAR-γ agonistic activity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 849206-43-5
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性状 Solid
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分子量 428.49
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分子式 C24H24N6O2
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Color White to off-white
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SMILES
O=C1OC(C)(C)C2=C1N(CC3=CC=C(C4=CC=CC=C4C5=NNN=N5)C=C3)C(CCC)=N2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (291.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Shah S, et al.. Simultaneous Quantitative Analysis of Olmesartan Medoxomil and Amlodipine Besylate in Plasma by High-performance Liquid Chromatography Technique. Journal of young pharmacists : JYP. 2012 Apr;4(2):88-94. [Content Brief]
[2]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. Journal of pharmacological sciences. 2016 Jul;131(3):190-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3338 mL | 11.6689 mL | 23.3378 mL | 58.3444 mL |
| 5 mM | 0.4668 mL | 2.3338 mL | 4.6676 mL | 11.6689 mL | |
| 10 mM | 0.2334 mL | 1.1669 mL | 2.3338 mL | 5.8344 mL | |
| 15 mM | 0.1556 mL | 0.7779 mL | 1.5559 mL | 3.8896 mL | |
| 20 mM | 0.1167 mL | 0.5834 mL | 1.1669 mL | 2.9172 mL | |
| 25 mM | 0.0934 mL | 0.4668 mL | 0.9335 mL | 2.3338 mL | |
| 30 mM | 0.0778 mL | 0.3890 mL | 0.7779 mL | 1.9448 mL | |
| 40 mM | 0.0583 mL | 0.2917 mL | 0.5834 mL | 1.4586 mL | |
| 50 mM | 0.0467 mL | 0.2334 mL | 0.4668 mL | 1.1669 mL | |
| 60 mM | 0.0389 mL | 0.1945 mL | 0.3890 mL | 0.9724 mL | |
| 80 mM | 0.0292 mL | 0.1459 mL | 0.2917 mL | 0.7293 mL | |
| 100 mM | 0.0233 mL | 0.1167 mL | 0.2334 mL | 0.5834 mL |
Olmesartan lactone impurity 関連分類
HY-131276 関連分類
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