849206-43-5
849206-43-5
Chemical Structure
Olmesartan lactone impurity
- CAS No.: 849206-43-5
- Formula:C24H24N6O2
- Molecular Weight:428.49
IUPAC Name: 3-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-6,6-dimethyl-2-propyl-3,6-dihydro-4H-furo[3,4-d]imidazol-4-one
InChIKey: JUQNVWFXORBZQJ-UHFFFAOYSA-N
SMILES: O=C1OC(C)(C)C2=C1N(CC3=CC=C(C4=CC=CC=C4C5=NNN=N5)C=C3)C(CCC)=N2
Biological Activity: Olmesartan lactone impurity is an impurity of Olmesartan (HY-17004). Olmesartan is an angiotensin II receptor (AT1R) antagonist that is used in hypertension research[1][2].
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Olmesartan lactone impurity | 99.27% | Olmesartan lactone impurity is an impurity of Olmesartan (HY-17004). Olmesartan is an angiotensin II receptor (AT1R) antagonist that is used in hypertension research. | ||||||||||||||||||||
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Olmesartan lactone impurity (Standard) | ≥98% | Olmesartan lactone impurity (Standard) is the analytical standard of Olmesartan lactone impurity. This product is intended for research and analytical applications. Olmesartan lactone impurity is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study. | ||||||||||||||||||||
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References
- [1]. Shah S, et al.. Simultaneous Quantitative Analysis of Olmesartan Medoxomil and Amlodipine Besylate in Plasma by High-performance Liquid Chromatography Technique. Journal of young pharmacists : JYP. 2012 Apr;4(2):88-94. [Content Brief]
- [2]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. Journal of pharmacological sciences. 2016 Jul;131(3):190-7. [Content Brief]
