RID-F
RID-F (Ridaifen-F), a Tamoxifen (HY-13757A) derivative, is a nonpeptidic proteasome inhibitor. RID-F inhibits human 20S proteasome activity, with IC50s of 0.64, 0.34, and 0.43 μM for CT-L, T-L, and PGPH, respectively.
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- CAS 番号: 1020853-03-5
- 分子式: C38H50N2O2
- 分子量:566.82
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | CC50 |
4.38 μM
Compound: 6, RID-F, Ridaifen-F
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Cytotoxicity against ER-negative HEK293 cells after 48 hrs by MTT assay
Cytotoxicity against ER-negative HEK293 cells after 48 hrs by MTT assay
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[PMID: 24321833] |
| HL-60 | CC50 |
3.42 μM
Compound: 6, RID-F, Ridaifen-F
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Cytotoxicity against ER-positive human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against ER-positive human HL60 cells after 48 hrs by MTT assay
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[PMID: 24321833] |
| RPMI-8226 | CC50 |
3.6 μM
Compound: 1
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Cytotoxicity against human RPMI8226 cells after 24 to 48 hrs by CellTiter-Glo assay
Cytotoxicity against human RPMI8226 cells after 24 to 48 hrs by CellTiter-Glo assay
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[PMID: 29407987] |
化学情報
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CAS 番号 1020853-03-5
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分子量 566.82
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分子式 C38H50N2O2
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SMILES
CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN3CCCCCC3)C=C2)\C4=CC=C(OCCN5CCCCCC5)C=C4
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別名
Ridaifen-F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
RID-F 関連分類
HY-113824 関連分類
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