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Satralizumab

(別名: RG-6168; SA-237)
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Based on 1 Customer Validation

Satralizumab is a humanized monoclonal antibody that targets IL-6R. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 99.82%
  • CAS 番号: 1535963-91-7
  • 分子量:144.5 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Satralizumab
  • Experimental Validation Results for Satralizumab
  • Experimental Validation Results for Satralizumab
  • Satralizumab Chemical Structure
    Satralizumab 構造式
CAS 番号: 1535963-91-7
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized hIL-6R-his can bind Satralizumab. The EC50 for this effect is 8.675 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 U937 cells with Satralizumab (HY-P99112, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Satralizumab Chemical Structure
    1/16
  • Satralizumab
  • Immobilized hIL-6R-his can bind Satralizumab. The EC50 for this effect is 8.675 ng/mL.
  • Flow cytometric analysis of 1.5×106 U937 cells with Satralizumab (HY-P99112, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa Isotype Control (HY-P99002, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).