Succinic acid-d6
Based on 1 Customer Validation
Succinic acid-d6 is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.0%
- CAS 番号: 21668-90-6
- 分子式: C4D6O4
- 分子量:124.13
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 21668-90-6
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非標識Cas 110-15-6
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性状 Solid
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分子量 124.13
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分子式 C4D6O4
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Color White to off-white
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SMILES
[2H]OC(C([2H])([2H])C([2H])([2H])C(O[2H])=O)=O
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別名
Wormwood acid-d6
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (805.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
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- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Zhang YJ, et al. Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM). J Zhejiang Univ Sci B. 2012 Feb;13(2):103-10. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.0561 mL | 40.2804 mL | 80.5607 mL | 201.4018 mL |
| 5 mM | 1.6112 mL | 8.0561 mL | 16.1121 mL | 40.2804 mL | |
| 10 mM | 0.8056 mL | 4.0280 mL | 8.0561 mL | 20.1402 mL | |
| 15 mM | 0.5371 mL | 2.6854 mL | 5.3707 mL | 13.4268 mL | |
| 20 mM | 0.4028 mL | 2.0140 mL | 4.0280 mL | 10.0701 mL | |
| 25 mM | 0.3222 mL | 1.6112 mL | 3.2224 mL | 8.0561 mL | |
| 30 mM | 0.2685 mL | 1.3427 mL | 2.6854 mL | 6.7134 mL | |
| 40 mM | 0.2014 mL | 1.0070 mL | 2.0140 mL | 5.0350 mL | |
| 50 mM | 0.1611 mL | 0.8056 mL | 1.6112 mL | 4.0280 mL | |
| 60 mM | 0.1343 mL | 0.6713 mL | 1.3427 mL | 3.3567 mL | |
| 80 mM | 0.1007 mL | 0.5035 mL | 1.0070 mL | 2.5175 mL | |
| 100 mM | 0.0806 mL | 0.4028 mL | 0.8056 mL | 2.0140 mL |