TRIA-662-d3
Based on 1 Customer Validation
TRIA-662-d3 is the deuterium labeled TRIA-662. TRIA-662 (1-Methylnicotinamide chloride) is an endogenous metabolite. TRIA-662 shows antithrombotic and anti-inflammatory activities.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.60%
- CAS 番号: 1218993-18-0
- 分子式: C7H6D3ClN2O
- 分子量:175.63
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 1218993-18-0
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非標識Cas 1005-24-9
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性状 Solid
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分子量 175.63
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分子式 C7H6D3ClN2O
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Color Off-white to light yellow
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SMILES
[2H]C([N+]1=CC=CC(C(N)=O)=C1)([2H])[2H].[Cl-]
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別名
1-Methylnicotinamide-d3chloride
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
H2O : 100 mg/mL (569.38 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. A M Kolodziejczyk, et al. Nanomechanical sensing of the endothelial cell response to anti-inflammatory action of 1-methylnicotinamide chloride. Int J Nanomedicine. 2013;8:2757-67. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.6938 mL | 28.4689 mL | 56.9379 mL | 142.3447 mL |
| 5 mM | 1.1388 mL | 5.6938 mL | 11.3876 mL | 28.4689 mL | |
| 10 mM | 0.5694 mL | 2.8469 mL | 5.6938 mL | 14.2345 mL | |
| 15 mM | 0.3796 mL | 1.8979 mL | 3.7959 mL | 9.4896 mL | |
| 20 mM | 0.2847 mL | 1.4234 mL | 2.8469 mL | 7.1172 mL | |
| 25 mM | 0.2278 mL | 1.1388 mL | 2.2775 mL | 5.6938 mL | |
| 30 mM | 0.1898 mL | 0.9490 mL | 1.8979 mL | 4.7448 mL | |
| 40 mM | 0.1423 mL | 0.7117 mL | 1.4234 mL | 3.5586 mL | |
| 50 mM | 0.1139 mL | 0.5694 mL | 1.1388 mL | 2.8469 mL | |
| 60 mM | 0.0949 mL | 0.4745 mL | 0.9490 mL | 2.3724 mL | |
| 80 mM | 0.0712 mL | 0.3559 mL | 0.7117 mL | 1.7793 mL | |
| 100 mM | 0.0569 mL | 0.2847 mL | 0.5694 mL | 1.4234 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
TRIA-662-d3 関連分類
HY-113527S 関連分類
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