TRIA-662 iodide
Based on 1 publication(s) in Google Scholar
TRIA-662 (1-Methylnicotinamide chloride) iodide is an endogenous metabolite. TRIA-662 iodide shows antithrombotic and anti-inflammatory activities.
For research use only. We do not sell to patients.
- Purity: 99.78%
- CAS No.: 6456-44-6
- Formula: C7H9IN2O
- Molecular Weight:264.06
-
Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Immunology/Inflammation Compound Library
HY-L007
-
Metabolism/Protease Compound Library
HY-L012
-
Human Endogenous Metabolite Compound Library
HY-L030
-
Anti-Cardiovascular Disease Compound Library
HY-L046
-
Animal-Sourced Natural Product Library
HY-L157
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
-
MCE Kinase Hinge Binder Fragment Library
HY-L907
Publications Citing Use of MedChemExpress (MCE) TRIA-662 iodide
MoreAll Endogenous Metabolite Isoforms
More
Biological Activity
|
Human Endogenous Metabolite |
Chemical Information
-
CAS No. 6456-44-6
-
Appearance Solid
-
Molecular Weight 264.06
-
Formula C7H9IN2O
-
Color Off-white to light yellow
-
SMILES
C[N+]1=CC=CC(C(N)=O)=C1.[I-]
-
Synonyms
1-Methylnicotinamide iodide
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Publications (1)
-
Journal Impact Factor
-
Most Recent
Solvent & Solubility
DMSO : 66.67 mg/mL (252.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (18.94 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7870 mL | 18.9351 mL | 37.8702 mL | 94.6755 mL |
| 5 mM | 0.7574 mL | 3.7870 mL | 7.5740 mL | 18.9351 mL | |
| 10 mM | 0.3787 mL | 1.8935 mL | 3.7870 mL | 9.4675 mL | |
| 15 mM | 0.2525 mL | 1.2623 mL | 2.5247 mL | 6.3117 mL | |
| 20 mM | 0.1894 mL | 0.9468 mL | 1.8935 mL | 4.7338 mL | |
| 25 mM | 0.1515 mL | 0.7574 mL | 1.5148 mL | 3.7870 mL | |
| 30 mM | 0.1262 mL | 0.6312 mL | 1.2623 mL | 3.1558 mL | |
| 40 mM | 0.0947 mL | 0.4734 mL | 0.9468 mL | 2.3669 mL | |
| 50 mM | 0.0757 mL | 0.3787 mL | 0.7574 mL | 1.8935 mL | |
| 60 mM | 0.0631 mL | 0.3156 mL | 0.6312 mL | 1.5779 mL | |
| 80 mM | 0.0473 mL | 0.2367 mL | 0.4734 mL | 1.1834 mL | |
| 100 mM | 0.0379 mL | 0.1894 mL | 0.3787 mL | 0.9468 mL |
TRIA-662 iodide Related Classifications
HY-W009418 Related Classifications
Powered by Bioz