UniPR505
Based on 1 Customer Validation
UniPR505 (Compound 14) is an EphA2 antagonist with an IC50 of 0.95 µM. UniPR505 displays anti-angiogenic properties.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.68%
- CAS 番号: 2938227-14-4
- 分子式: C39H57N3O5
- 分子量:647.89
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
IC50: 0.95 µM (EphA2), 4.4 µM (EphA5), 4.5 µM (EphA3), 6.4 µM (EphA4), 7.7 µM (EphA8), 11 µM (EphB3), 14 µM (EphB2), 18 µM (EphA6)[1]
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Cell Line
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Type | Value | Description | References |
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| HUVEC | IC50 |
3 μM
Compound: 14
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Antiangiogenic activity in HUVEC assessed as reduction in number of polygons formation after 16 hrs by matrigel-based microscopic analysis
Antiangiogenic activity in HUVEC assessed as reduction in number of polygons formation after 16 hrs by matrigel-based microscopic analysis
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[PMID: 32000051] |
化学情報
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CAS 番号 2938227-14-4
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性状 Solid
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分子量 647.89
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分子式 C39H57N3O5
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Color White to off-white
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SMILES
[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@@H]([C@]4(CC[C@]3([H])[C@]1(CC[C@H](C2)OC(NCC)=O)C)C)[C@@H](CCC(N[C@@H](CC5=CNC6=C5C=CC=C6)CC(O)=O)=O)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (154.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5435 mL | 7.7174 mL | 15.4347 mL | 38.5868 mL |
| 5 mM | 0.3087 mL | 1.5435 mL | 3.0869 mL | 7.7174 mL | |
| 10 mM | 0.1543 mL | 0.7717 mL | 1.5435 mL | 3.8587 mL | |
| 15 mM | 0.1029 mL | 0.5145 mL | 1.0290 mL | 2.5725 mL | |
| 20 mM | 0.0772 mL | 0.3859 mL | 0.7717 mL | 1.9293 mL | |
| 25 mM | 0.0617 mL | 0.3087 mL | 0.6174 mL | 1.5435 mL | |
| 30 mM | 0.0514 mL | 0.2572 mL | 0.5145 mL | 1.2862 mL | |
| 40 mM | 0.0386 mL | 0.1929 mL | 0.3859 mL | 0.9647 mL | |
| 50 mM | 0.0309 mL | 0.1543 mL | 0.3087 mL | 0.7717 mL | |
| 60 mM | 0.0257 mL | 0.1286 mL | 0.2572 mL | 0.6431 mL | |
| 80 mM | 0.0193 mL | 0.0965 mL | 0.1929 mL | 0.4823 mL | |
| 100 mM | 0.0154 mL | 0.0772 mL | 0.1543 mL | 0.3859 mL |
UniPR505 関連分類
HY-146375 関連分類
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