KRT3 - keratin 3 Gene

Also Known as K3; CK3; MECD2

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 3850

About KRT3

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:52,789,685-52,796,117 (from NCBI)

This gene has 1 transcript (splice variant), 72 orthologues, 68 paralogues and is associated with 3 phenotypes. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]

KRT3 Products (1)

mRNA	Protein	Name
NM_057088.3	NP_476429.2	keratin, type II cytoskeletal 3

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in intermediate filament cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	9171831	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KRT3 Protein Structure

Filament

0
100
200
300
400
500
628 a.a.

Protein Preferred Names	Protein Names
keratin, type II cytoskeletal 3	65 kDa cytokeratin

KRT3 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	KRT3	P12035	g4xuv3_human	Homo sapiens	G4XUV3	Y2H Array	32296183
Intra	KRT3	P12035	g4xuv3_human	Homo sapiens	G4XUV3	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT37	Homo sapiens	O76014	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	KRT3	P12035	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT38	Homo sapiens	O76015	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT38	Homo sapiens	O76015	Y2H Array	32296183
Intra	KRT3	P12035	KRT33B	Homo sapiens	Q14525	Y2H Array	32296183
Intra	KRT3	P12035	KRT33B	Homo sapiens	Q14525	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT33B	Homo sapiens	Q14525	Validated Y2H	32296183
Intra	KRT3	P12035	KRT35	Homo sapiens	Q92764	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT35	Homo sapiens	Q92764	Validated Y2H	32296183
Intra	KRT3	P12035	KRT35	Homo sapiens	Q92764	Y2H Array	32296183
Intra	KRT3	P12035	KRTAP13-2	Homo sapiens	Q52LG2	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRTAP13-2	Homo sapiens	Q52LG2	Validated Y2H	32296183
Intra	KRT3	P12035	KRTAP13-2	Homo sapiens	Q52LG2	Y2H Array	32296183
Intra	KRT3	P12035	KRT39	Homo sapiens	Q6A163	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT39	Homo sapiens	Q6A163	Y2H Array	32296183
Intra	KRT3	P12035	KRT39	Homo sapiens	Q6A163	Validated Y2H	32296183
Intra	KRT3	P12035	KRT36	Homo sapiens	O76013-2	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT36	Homo sapiens	O76013-2	Y2H Array	32296183
Intra	KRT3	P12035	KRT25	Homo sapiens	Q7Z3Z0	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT25	Homo sapiens	Q7Z3Z0	Validated Y2H	32296183
Intra	KRT3	P12035	KRT25	Homo sapiens	Q7Z3Z0	Y2H Array	32296183
Intra	KRT3	P12035	KRT28	Homo sapiens	Q7Z3Y7	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT28	Homo sapiens	Q7Z3Y7	Y2H Array	32296183
Intra	KRT3	P12035	KRT28	Homo sapiens	Q7Z3Y7	Validated Y2H	32296183
Intra	KRT3	P12035	LHX3	Homo sapiens	Q9UBR4-2	Validated Y2H	32296183
Intra	KRT3	P12035	LHX3	Homo sapiens	Q9UBR4-2	Y2H Array	32296183
Intra	KRT3	P12035	LHX3	Homo sapiens	Q9UBR4-2	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	WWOX	Homo sapiens	Q9NZC7-5	Y2H Array	32296183
Intra	KRT3	P12035	WWOX	Homo sapiens	Q9NZC7-5	Validated Y2H	32296183
Intra	KRT3	P12035	WWOX	Homo sapiens	Q9NZC7-5	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT26	Homo sapiens	Q7Z3Y9	Validated Y2H	32296183
Intra	KRT3	P12035	KRT26	Homo sapiens	Q7Z3Y9	Y2H Array	32296183
Intra	KRT3	P12035	KRT26	Homo sapiens	Q7Z3Y9	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KIFC3	Homo sapiens	Q9BVG8-5	Validated Y2H	32296183
Intra	KRT3	P12035	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Array	32296183
Intra	KRT3	P12035	TRIM54	Homo sapiens	Q9BYV2	Y2H Array	32296183
Intra	KRT3	P12035	TRIM54	Homo sapiens	Q9BYV2	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	TRIM54	Homo sapiens	Q9BYV2	Validated Y2H	32296183
Intra	KRT3	P12035	HAUS1	Homo sapiens	Q96CS2	Validated Y2H	32296183
Intra	KRT3	P12035	HAUS1	Homo sapiens	Q96CS2	Y2H Array	32296183
Intra	KRT3	P12035	HAUS1	Homo sapiens	Q96CS2	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	SAPCD2	Homo sapiens	Q86UD0	Validated Y2H	32296183
Intra	KRT3	P12035	SAPCD2	Homo sapiens	Q86UD0	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	SAPCD2	Homo sapiens	Q86UD0	Y2H Array	32296183
Intra	KRT3	P12035	C3orf62	Homo sapiens	Q6ZUJ4	Validated Y2H	32296183
Intra	KRT3	P12035	C3orf62	Homo sapiens	Q6ZUJ4	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	C3orf62	Homo sapiens	Q6ZUJ4	Y2H Array	32296183
Intra	KRT3	P12035	KRT75	Homo sapiens	O95678	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT75	Homo sapiens	O95678	Y2H Array	32296183
Intra	KRT3	P12035	KRT24	Homo sapiens	Q2M2I5	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT24	Homo sapiens	Q2M2I5	Validated Y2H	32296183
Intra	KRT3	P12035	KRT24	Homo sapiens	Q2M2I5	Y2H Array	32296183
Intra	KRT3	P12035	KRT27	Homo sapiens	Q7Z3Y8	Y2H Array	32296183
Intra	KRT3	P12035	KRT27	Homo sapiens	Q7Z3Y8	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT27	Homo sapiens	Q7Z3Y8	Validated Y2H	32296183
Intra	KRT3	P12035	NUP62	Homo sapiens	P37198	Validated Y2H	32296183
Intra	KRT3	P12035	NUP62	Homo sapiens	P37198	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	NUP62	Homo sapiens	P37198	Y2H Array	32296183
Intra	KRT3	P12035	KRT16	Homo sapiens	P08779	Y2H Array	32296183
Intra	KRT3	P12035	KRT16	Homo sapiens	P08779	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	TRAF1	Homo sapiens	Q13077	Y2H Array	32296183
Intra	KRT3	P12035	TRAF1	Homo sapiens	Q13077	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	TRAF1	Homo sapiens	Q13077	Validated Y2H	32296183
Intra	KRT3	P12035	SPAG5	Homo sapiens	Q96R06	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	SPAG5	Homo sapiens	Q96R06	Y2H Array	32296183
Intra	KRT3	P12035	SPAG5	Homo sapiens	Q96R06	Validated Y2H	32296183
Intra	KRT3	P12035	OIP5	Homo sapiens	O43482	Y2H Array	32296183
Intra	KRT3	P12035	OIP5	Homo sapiens	O43482	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT14	Homo sapiens	P02533	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT14	Homo sapiens	P02533	Y2H Array	32296183
Intra	KRT3	P12035	TRIM27	Homo sapiens	P14373	Y2H Array	32296183
Intra	KRT3	P12035	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	TRIM27	Homo sapiens	P14373	Validated Y2H	32296183
Intra	KRT3	P12035	HGS	Homo sapiens	O14964	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	HGS	Homo sapiens	O14964	Y2H Array	32296183
Intra	KRT3	P12035	LURAP1	Homo sapiens	Q96LR2	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	LURAP1	Homo sapiens	Q96LR2	Validated Y2H	32296183
Intra	KRT3	P12035	LURAP1	Homo sapiens	Q96LR2	Y2H Array	32296183
Intra	KRT3	P12035	KRT20	Homo sapiens	P35900	Validated Y2H	32296183
Intra	KRT3	P12035	KRT19	Homo sapiens	P08727	Y2H Array	32296183
Intra	KRT3	P12035	KRT19	Homo sapiens	P08727	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	ZNF426	Homo sapiens	Q9BUY5	Y2H Array	32296183
Intra	KRT3	P12035	ZNF426	Homo sapiens	Q9BUY5	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	ZNF426	Homo sapiens	Q9BUY5	Validated Y2H	32296183
Intra	KRT3	P12035	DEUP1	Homo sapiens	Q05D60	Validated Y2H	32296183
Intra	KRT3	P12035	DEUP1	Homo sapiens	Q05D60	Y2H Array	32296183
Intra	KRT3	P12035	DEUP1	Homo sapiens	Q05D60	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	CCDC197	Homo sapiens	Q8NCU1	Y2H Array	32296183
Intra	KRT3	P12035	CCDC197	Homo sapiens	Q8NCU1	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	CCDC197	Homo sapiens	Q8NCU1	Validated Y2H	32296183
Intra	KRT3	P12035	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	KRT31	Homo sapiens	Q15323	Validated Y2H	32296183
Intra	KRT3	P12035	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	KRT3	P12035	PLEKHG4	Homo sapiens	Q58EX7	Validated Y2H	32296183
Intra	KRT3	P12035	PLEKHG4	Homo sapiens	Q58EX7	Y2H Array	32296183
Intra	KRT3	P12035	PLEKHG4	Homo sapiens	Q58EX7	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	BPIFA1	Homo sapiens	Q9NP55	Y2H Prey Pooling	32296183
Intra	KRT3	P12035	BPIFA1	Homo sapiens	Q9NP55	Y2H Array	32296183
Intra	KRT3	P12035	BPIFA1	Homo sapiens	Q9NP55	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Corneal Dystrophy, Meesmann, 2	Meesmann Corneal Dystrophy 2 MECD2 Corneal Dystrophy, Meesmann 2
Corneal Dystrophy, Meesmann, 1	Meesmann Corneal Dystrophy Mecd Corneal Dystrophy, Meesmann Epithelial Juvenile Hereditary Epithelial Dystrophy Corneal Dystrophy, Juvenile Epithelial Of Meesmann MECD1 Meesmann Corneal Dystrophy 1 Meesmann Corneal Epithelial Dystrophy Meesmann Epithelial Corneal Dystrophy Corneal Dystrophy, Juvenile Epithelial, Of Meesmann Stocker-Holt Dystrophy Meesman Dystrophy Meesman'S Corneal Dystrophy Juvenile Hereditary Epithelial Dystrophy Of Meesmann Corneal Dystrophy, Meesmann 1 Juvenile Epithelial Corneal Dystrophy Of Meesmann Mcd Dystrophy, Corneal, Meesmann
Corneal Dystrophy
Corneal Disease	Corneal Diseases Corneal Disorders
Keratoconus	Kc Conical Cornea Noninflammatory Corneal Thining Bulging Cornea Cornea Conical Acquired Conus Of Cornea
Cicatricial Entropion
Astigmatism
Corneal Endothelial Dystrophy	Congenital Hereditary Endothelial Dystrophy Of Cornea Chandler Syndrome CHED Chandler'S Syndrome Endothelial Corneal Dystrophy Ched2 Maumenee Corneal Dystrophy Corneal Dystrophy, Congenital Hereditary Endothelial Dystrophy Of Corneal Endothelium Corneal Endothelial Dystrophy 2 Corneal Endothelial Dystrophy 2, Autosomal Recessive, Formerly Ched2, Formerly Corneal Endothelial Dystrophy, Autosomal Recessive Endothelial Dystrophy Posterior Membrane Corneal Dystrophy Corneal Endothelial Dystrophy Type 2 Congenital Hereditary Endothelial Dystrophy Of The Cornea Congenital Hereditary Endothelial Dystrophy Type Ii Autosomal Recessive Ched Autosomal Recessive Congenital Hereditary Endothelial Dystrophy Chedii Congenital Hereditary Endothelial Dystrophy Type 2 Infantile Hereditary Endothelial Dystrophy Congenital Hereditary Endothelial Corneal Dystrophy Corneal Endothelial Dystrophy 2, Autosomal Recessive Iridocorneal Endothelial Syndrome Dystrophy, Corneal, Endothelial Corneal Endothelial Dystrophy 1, Autosomal Dominant
Epithelial And Subepithelial Dystrophy
Recurrent Corneal Erosion	Recurrent Erosion Of Cornea Recurrent Erosion Syndrome Corneal Erosion Non-Traumatic Recurrent Erosion Of Cornea
Corneal Dystrophy, Lisch Epithelial	Lisch Epithelial Corneal Dystrophy LECD Band-Shaped And Whorled Microcystic Corneal Epithelial Dystrophy Band-Shaped And Whorled Microcystic Band-Shaped And Whorled Microcystic Dystrophy Of The Corneal Epithelium
Corneal Deposit	Deposits - Cornea
Granular Corneal Dystrophy	Granular Dystrophy Corneal Corneal Dystrophies, Hereditary Hereditary Corneal Dystrophy Corneal Dystrophy Nos Familial Hereditary Corneal Degeneration Hereditary Corneal Opacity
Hymenolepiasis	Dwarf Tapeworm Infection Hymenolepis Infectious Disease Hymenolepsis Infection Hyemolepis Nana Infection Hymenolepiosis Hymenolepis Infection Dwarf Tapeworm Hymenolepidosis Hymenolepis Infestation
Filamentary Keratitis
Corneal Dystrophy, Thiel-Behnke Type	Thiel-Behnke Corneal Dystrophy Tbcd CDTB Cdb2 Corneal Dystrophy Of Bowman Layer Type Ii Anterior Limiting Membrane Dystrophy Type Ii Waardenburg-Jonker Corneal Dystrophy Corneal Dystrophy Of Bowman Layer, Type Ii Corneal Dystrophy, Honeycomb-Shaped Corneal Dystrophy Honeycomb-Shaped Corneal Dystrophy Thiel Behnke Type Corneal Dystrophy Honeycomb Shaped Corneal Dystrophy Of The Bowman Layer Type 2 Thiel Behnke Corneal Dystrophy Anterior Limiting Membrane Dystrophy Type 2 Corneal Dystrophy Of Bowman Layer Type 2 Curly Fiber Corneal Dystrophy Honeycomb Corneal Dystrophy Honeycomb-Shaped Corneal Dystrophy Dystrophy, Corneal, Thiel-Behnke Type
Pseudopterygium
Corneal Dystrophy, Reis-Bucklers Type	Reis-Bucklers Corneal Dystrophy Rbcd CDRB Cdb1 Corneal Dystrophy Of Bowman Layer Type I Geographic Corneal Dystrophy Granular Corneal Dystrophy Type Iii Reis-Bucklers' Corneal Dystrophy Anterior Limiting Membrane Dystrophy Type I Corneal Dystrophy Of Bowman Layer Type 1 Corneal Dystrophy Of Bowman Layer, Type I Corneal Dystrophy, Geographic Granular Corneal Dystrophy, Type Iii Corneal Dystrophy Reis Bucklers Type Corneal Dystrophy Geographic Reis Bucklers Corneal Dystrophy Reis Bucklers Dystrophy Anterior Limiting Membrane Dystrophy Type 1 Atypical Granular Corneal Dystrophy Granular Corneal Dystrophy Type 3 Superficial Granular Corneal Dystrophy Corneal Dystrophy Of Bowman Layer, Type 1 Dystrophy, Corneal, Reis-Bucklers Type
Anterior Scleritis
Punctate Epithelial Keratoconjunctivitis	Punctate Keratitis Thygeson Superficial Punctate Keratitis Thygeson'S Superficial Punctate Keratitis Thygeson Superficial Punctate Keratopathy Punctate Epithelial Keratitis
Keratopathy
Corneal Dystrophy, Avellino Type	Avellino Corneal Dystrophy CDA Combined Granular-Lattice Corneal Dystrophy Cgd2 Granular Corneal Dystrophy Type 2 Acd Granular Corneal Dystrophy 2 Corneal Dystrophy Avellino Type Granular Corneal Dystrophy Type Ii Granular Corneal Dystrophy, Type Ii Combined Granular-Lattice Corneal Dystrophies Granular And Lattice Corneal Dystrophies Granular-Lattice Corneal Dystrophy Gcd2 Gcdii Granular-Lattice Corneal Dystrophy
Corneal Dystrophy, Gelatinous Drop-Like	Gelatinous Drop-Like Corneal Dystrophy GDLD Cdgdl Corneal Amyloidosis Lattice Corneal Dystrophy Type Iii Amyloidosis, Corneal Amyloid Corneal Dystrophy, Japanese Type Gdcd Primary Familial Amyloidosis Of The Cornea Subepithelial Amyloidosis Of The Cornea Corneal Dystrophy, Lattice Type 3 Corneal Dystrophy, Lattice Type Iii Lattice Corneal Dystrophy, Type Iii Amyloidosis Corneal Lattice Corneal Dystrophy Type3 Amyloid Corneal Dystrophy Japanese Type Dystrophy, Corneal, Gelatinous Drop-Like Amyloid Of Cornea
Cicatricial Pemphigoid	Mucous Membrane Pemphigoid Ocular Pemphigoid Benign Mucous Membrane Pemphigoid Benign Mucous Membrane Pemphigoid With Ocular Involvement Benign Mucosal Pemphigoid Pemphigoid, Benign Mucous Membrane Cicatricial Pemphigoid With Ocular Involvement Ocular Pemphigus Cicatricial Pemphigoid Disease Mucosal Pemphigoid Mucosynechial Pemphigoid Pemphigoid Cicatricial Cicatricial Pemphigoid Involving The Eye Ocular Cicatricial Pemphigoid
Macular Dystrophy, Corneal	Macular Corneal Dystrophy MCD Corneal Dystrophy, Macular Type Groenouw Type Ii Corneal Dystrophy Fehr Corneal Dystrophy Macular Dystrophy, Corneal Type 1 Mcdc1 Macular Corneal Dystrophy Type Ii Macular Corneal Dystrophy, Type Ii Macular Corneal Dystrophy, Type I Mcdc1, Formerly Macular Dystrophy, Corneal, 1 Macular Corneal Dystrophy Type 1 Corneal Dystrophy Groenouw Type Ii Corneal Dystrophy Macular Type Macular Corneal Dystrophy Type I Dystrophy, Macular, Corneal
Epithelial Basement Membrane Dystrophy	Ebmd Corneal Dystrophy, Epithelial Basement Membrane Cogan Corneal Dystrophy Microcystic Corneal Dystrophy Anterior Basement Membrane Dystrophy Cogan Microcystic Epithelial Dystrophy Map-Dot-Fingerprint Dystrophy Microscopic Cystic Corneal Dystrophy
Plica Syndrome	Synovitis
Severe Cutaneous Adverse Reaction	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Drug-Induced Stevens Johnson Syndrome Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum Susceptibility To Severe Cutaneous Adverse Reaction Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Lyell'S Syndrome Lyell Syndrome Severe Cutaneous Adverse Reaction, Susceptibility To Hypersensitivity Syndrome, Carbamazepine-Induced, Susceptibility To Hypersensitivity Syndrome, Carbamazepine-Induced Stevens-Johnson Syndrome, Susceptibility To Toxic Epidermal Necrolysis, Susceptibility To Sjs/Ten Susceptibility To Severe Cutaneous Adverse Reaction Ity To Mycoplasma-Induced Stevens Johnson Syndrome Dermatostomatitis, Stevens Johnson Type Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Spectrum Sjs-Ten Toxic Epidermolysis SJS Dermatostomatitis Stevens Johnson Type Ten Sjs/Ten - [Stevens-Johnson Syndrome And Toxic Epidermal Necrolysis] Ten - [Toxic Epidermal Necrolysis]
Schnyder Corneal Dystrophy	Schnyder Crystalline Corneal Dystrophy SCCD Corneal Dystrophy, Crystalline, Of Schnyder Corneal Dystrophy, Schnyder Type Corneal Dystrophy Crystalline Of Schnyder Crystalline Stromal Dystrophy Hereditary Crystalline Stromal Dystrophy Of Schnyder Scd Corneal Dystrophy, Schnyder Schnyder Crystalline Dystrophy Sine Crystals Dystrophy, Corneal, Crystalline, Schnyder
Congenital Disorder Of Glycosylation, Type Iic	CDG2C Congenital Disorder Of Glycosylation Type Iic Leukocyte Adhesion Deficiency Type Ii Cdg Iic Cdgiic Rambam-Hasharon Syndrome Leukocyte Adhesion Deficiency, Type Ii Lad2 Leukocyte Adhesion Deficiency 2 Cdg-Iic Congenital Disorder Of Glycosylation, Type 2c Rhs Cdg Syndrome Type Iic Lad-Ii Rambam Hasharon Syndrome Congenital Disorder Of Glycosylation 2c Glycosylation, Congenital Disorder Of, Type Iic
Deep Keratitis
Interstitial Keratitis
Entropion
Epithelial-Stromal Tgfbi Dystrophy
Orbital Granuloma
Corneal Degeneration	Degenerative Corneal Opacity
Corneal Ulcer	Cornea Ulcer Ulcerative Keratitis Corneal Ulcer Nos
Aniridia 1	Aniridia Congenital Aniridia AN1 An Cataract With Late-Onset Corneal Dystrophy Aplasia Of Iris Absent Iris Irideremia Aniridia Ii, Formerly An2, Formerly An2 Aniridia Type Ii Aniridia, Type 1 An-1 Absence Of Iris Agenesis Of Iris Congenital Absence Of Iris Hereditary Aniridia Sporadic Aniridia
Cardiac Valvular Dysplasia, X-Linked	Xmvd X-Linked Cardiac Valvular Dysplasia CVD1 Filamin A-Related X-Linked Myxomatous Valvular Dysplasia Flna-Related Valvular Dystrophy Flna-Related X-Linked Myxomatous Valvular Dysplasia Valvular Heart Disease, Congenital Myxomatous Valvular Dystrophy, X-Linked Congenital Valvular Heart Disease X-Linked Myxomatous Valvular Dystrophy CVDPX Ehlers-Danlos Syndrome, Type V, Formerly Eds5, Formerly Dystrophie Valvulaire Associee A Flna Eds 5 Ehlers-Danlos Syndrome, Type 5 Dystrophie Valvulaire Associée À Flna Filamin-A-Associated Myxomatous Mitral Valve Disease Filamin-A-Related Myxomatous Mitral Valve Dystrophy Congenital Valvular Dysplasia Cvdx Ehlers-Danlos Syndrome Type 5
Irregular Astigmatism
Corneal Dystrophy, Posterior Polymorphous, 1	Posterior Polymorphous Corneal Dystrophy Ppcd Maumenee Corneal Dystrophy Posterior Polymorphous Corneal Dystrophy 1 PPCD1 Corneal Dystrophy, Hereditary Polymorphous Posterior Corneal Endothelial Dystrophy 1, Autosomal Dominant Schlichting Dystrophy Ched1 Corneal Endothelial Dystrophy 1, Autosomal Dominant, Formerly Ched1, Formerly Hereditary Polymorphus Posterior Corneal Dystrophy Posterior Polymorphous Dystrophy Hereditary Polymorphous Posterior Corneal Dystrophy Dystrophy, Corneal, Posterior Polymorphous Dystrophy, Corneal, Posterior Polymorphous, Type 1 Polymorphous Corneal Dystrophy Corneal Endothelial Dystrophy 2
Iris Disease	Iris Diseases
Corneal Dystrophy, Subepithelial Mucinous	Subepithelial Mucinous Corneal Dystrophy SMCD
Corneal Edema	Corneal Oedema Infiltrate Of Cornea
Meibomian Cyst	Chalazion Meibomian Gland Lipogranuloma Tarsal Cyst
Hepatic Infarction	Infarct Of Liver Hepatic Infarct Liver Infarct Liver Infarction
Conjunctival Squamous Cell Carcinoma	Squamous Cell Carcinoma Of Conjunctiva Conjunctival Epidermoid Carcinoma Invasive Squamous Cell Carcinoma Of The Conjunctiva Ocular Surface Squamous Neoplasia
Stromal Dystrophy
Keratitis, Hereditary	Keratitis Autosomal Dominant Keratitis Hereditary Keratitis Dominantly Inherited Keratitis Keratitis Hereditary KERH
Keratosis Follicularis Spinulosa Decalvans	Kfsd Keratosis Follicularis Spinulosa Decalvans Cum Ophiasi Keratosis Follicularis Spinulosa Decalvans, X-Linked Keratosis Follicularis Spinulosa Decalvans, Autosomal Dominant
Tyrosinemia, Type Ii	Tyrosinemia Type Ii Oculocutaneous Tyrosinemia Richner-Hanhart Syndrome Tyrosine Aminotransferase Deficiency Tat Deficiency Tyrosine Transaminase Deficiency Keratosis Palmoplantaris With Corneal Dystrophy TYRSN2 Oregon Type Tyrosinemia Tyrosinemia Type 2 Tyrosinosis Oculocutaneous Type Tyrosinosis, Oculocutaneous Type Richner Hanhart Syndrome Keratosis Palmoplantaris-Corneal Dystrophy Syndrome Tyrosinemia Due To Tat Deficiency Tyrosinemia Due To Tyrosine Aminotransferase Deficiency Tyrosinemia 2 Tyrosinemia Oregon Type Tyrosine Transaminase Deficiency Disease
Fuchs' Endothelial Dystrophy	Fuchs Endothelial Corneal Dystrophy Fuchs Endothelial Dystrophy Fuchs Dystrophy Fced Fuchs' Corneal Dystrophy Fuchs' Endothelial Corneal Dystrophy Fuchs Atrophy Fuchs Corneal Dystrophy Endoepithelial Corneal Dystrophy Fecd Late Hereditary Endothelial Dystrophy Corneal Dystrophy, Fuchs Endothelial Dystrophy, Corneal, Fuchs Endothelial Corneal Dystrophy, Fuchs' Endothelial, 1
Breast Disease	Breast Diseases
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07450	KRT3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown