KRT28 - keratin 28 Gene

Also Known as KRT25D; K25IRS4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 162605

Summary

This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with Actin microfilaments and microtubules, compose the Cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
Low expression observed in reference dataset.

KRT28 Products (1)

mRNA Protein Name
NG_012419.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KRT28 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KRT28 Q7Z3Y7 CCDC196 Homo sapiens A0A1B0GWI1
Y2H Array
32296183
Intra
KRT28 Q7Z3Y7 CCDC196 Homo sapiens A0A1B0GWI1
Y2H Prey Pooling
32296183
Intra
KRT28 Q7Z3Y7 KRT79 Homo sapiens Q5XKE5
Y2H Array
32296183
Intra
KRT28 Q7Z3Y7 KRT79 Homo sapiens Q5XKE5
Y2H Prey Pooling
32296183
Intra
KRT28 Q7Z3Y7 NUP58 Homo sapiens Q9BVL2
Validated Y2H
32296183
Intra
KRT28 Q7Z3Y7 KRT5 Homo sapiens P13647
Y2H Prey Pooling
32296183
Intra
KRT28 Q7Z3Y7 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
Intra
KRT28 Q7Z3Y7 ABI3 Homo sapiens Q9P2A4
Validated Y2H
32296183
Intra
KRT28 Q7Z3Y7 KRT86 Homo sapiens O43790
Y2H Array
32296183
Intra
KRT28 Q7Z3Y7 KRT86 Homo sapiens O43790
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18137 Krt8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24612 Krt8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown