KRT79 - keratin 79 Gene

Also Known as K6L; KRT6L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 338785

About KRT79

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:52,821,408-52,834,311 (from NCBI)

This gene has 3 transcripts (splice variants), 84 orthologues and 68 paralogues. Biased expression in skin (RPKM 6.3), fat (RPKM 0.8) and 1 other tissue.

Summary

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in skeletal muscle, skin and scalp. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]

KRT79 Products (1)

mRNA Protein Name
NM_175834.3 NP_787028.1 keratin, type II cytoskeletal 79

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
23382074 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KRT79 Protein Structure

Filament

Filament: Intermediate filament protein (141 - 456)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 535 a.a.
Protein Preferred Names Protein Names

keratin, type II cytoskeletal 79

  • CK-79

KRT79 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
KRT79 Q5XKE5 KRT13 Homo sapiens A1A4E9
Y2H Prey Pooling
25416956
Intra
KRT79 Q5XKE5 KRT13 Homo sapiens A1A4E9
Y2H Array
25416956
Intra
KRT79 Q5XKE5 SYCE3 Homo sapiens A1L190
Y2H Array
32296183
Intra
KRT79 Q5XKE5 SYCE3 Homo sapiens A1L190
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT38 Homo sapiens O76015
Y2H Array
25416956
Intra
KRT79 Q5XKE5 KRT38 Homo sapiens O76015
Y2H Array
29892012
Intra
KRT79 Q5XKE5 KRT38 Homo sapiens O76015
Validated Y2H
25416956
Intra
KRT79 Q5XKE5 KRT33B Homo sapiens Q14525
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT33B Homo sapiens Q14525
Y2H Array
25416956
Intra
KRT79 Q5XKE5 KRT33B Homo sapiens Q14525
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT33B Homo sapiens Q14525
Y2H Array
31515488
Intra
KRT79 Q5XKE5 KRT35 Homo sapiens Q92764
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT35 Homo sapiens Q92764
Validated Y2H
32296183
Intra
KRT79 Q5XKE5 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT36 Homo sapiens O76013-2
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT36 Homo sapiens O76013-2
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT25 Homo sapiens Q7Z3Z0
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT25 Homo sapiens Q7Z3Z0
Validated Y2H
32296183
Intra
KRT79 Q5XKE5 KRT25 Homo sapiens Q7Z3Z0
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT28 Homo sapiens Q7Z3Y7
Validated Y2H
32296183
Intra
KRT79 Q5XKE5 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra
KRT79 Q5XKE5 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT24 Homo sapiens Q2M2I5
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT24 Homo sapiens Q2M2I5
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT18 Homo sapiens P05783
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT18 Homo sapiens P05783
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT27 Homo sapiens Q7Z3Y8
Validated Y2H
32296183
Intra
KRT79 Q5XKE5 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT27 Homo sapiens Q7Z3Y8
Complementation
32296183
Intra
KRT79 Q5XKE5 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT16 Homo sapiens P08779
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT16 Homo sapiens P08779
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT14 Homo sapiens P02533
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT14 Homo sapiens P02533
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT15 Homo sapiens P19012
Validated Y2H
25416956
Intra
KRT79 Q5XKE5 KRT15 Homo sapiens P19012
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT15 Homo sapiens P19012
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT15 Homo sapiens P19012
Y2H Prey Pooling
25416956
Intra
KRT79 Q5XKE5 USHBP1 Homo sapiens Q8N6Y0
Y2H Array
25416956
Intra
KRT79 Q5XKE5 KRT19 Homo sapiens P08727
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT19 Homo sapiens P08727
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 EVI5L Homo sapiens Q96CN4
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 EVI5L Homo sapiens Q96CN4
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
KRT79 Q5XKE5 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
KRT79 Q5XKE5 KRT31 Homo sapiens Q15323
Validated Y2H
25416956
Intra
KRT79 Q5XKE5 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07466 KRT79 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta KRT79 VGNC VGNC:74150
Rattus norvegicus KRT79 RGD RGD:1583372
Felis catus KRT79 VGNC VGNC:63173
Bos taurus KRT79 VGNC VGNC:30741
Mus musculus KRT79 MGD MGI:2385030
Canis familiaris KRT79 VGNC VGNC:42533
Others KRT79 NCBI