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Cat. No.: HY-161085

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BI 1265162

BI 1265162 is a potent inhibitor of endothelial sodium channel (ENaC) that plays an important role in cystic fibrosis research.

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CAS No.: 3042822-44-3
화학식: C₂₄H₃₆ClN₇O₉P₂
분자량:663.98

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

BI 1265162 Chemical Structure

CAS No.: 3042822-44-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Clinical Trial
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

BI 1265162 is a potent inhibitor of endothelial sodium channel (ENaC) that plays an important role in cystic fibrosis research^[1].

All Sodium Channel Isoforms :

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 3042822-44-3
분자량 663.98
화학식 C₂₄H₃₆ClN₇O₉P₂
SMILES

ClC1=CN=C(N)C(C(NCC2=[N+](CC)C(C=CC(OCC(NCCOCP(C)(C)=O)=O)=C3)=C3N2CC)=O)=N1.[O-]P(O)(O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bodo Betzemeier, et al. Discovery and development of BI 1265162, an ENaC inhibitor for the treatment of cystic fibrosis. European Journal of Medicinal Chemistry, 2023, 116038, ISSN 0223-5234,

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- Clinical Trial
Chemical Information
순도&문서
References

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BI 1265162

All Sodium Channel Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

BI 1265162 Related Classifications

HY-161085 Related Classifications