D-Sorbitol-13C6
Based on 1 Customer Validation
D-Sorbitol-13C6 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.94%
- CAS No.: 121067-66-1
- 화학식: 13C6H14O6
- 분자량:188.13
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 121067-66-1
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Unlabeled Cas 50-70-4
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Appearance Solid
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분자량 188.13
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화학식 13C6H14O6
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Color White to off-white
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SMILES
O[13CH2][13C@@H](O)[13C@@H](O)[13C@H](O)[13C@@H](O)[13CH2]O
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Synonyms
Sorbitol-13C6; D-Glucitol-13C6
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
H2O : 250 mg/mL (1328.87 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Ranjeet Prasad Dash, et al. Use of sorbitol as pharmaceutical excipient in the present day formulations - issues and challenges for drug absorption and bioavailability. Drug Dev Ind Pharm. 2019 Sep;45(9):1421-1429. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.3155 mL | 26.5774 mL | 53.1547 mL | 132.8868 mL |
| 5 mM | 1.0631 mL | 5.3155 mL | 10.6309 mL | 26.5774 mL | |
| 10 mM | 0.5315 mL | 2.6577 mL | 5.3155 mL | 13.2887 mL | |
| 15 mM | 0.3544 mL | 1.7718 mL | 3.5436 mL | 8.8591 mL | |
| 20 mM | 0.2658 mL | 1.3289 mL | 2.6577 mL | 6.6443 mL | |
| 25 mM | 0.2126 mL | 1.0631 mL | 2.1262 mL | 5.3155 mL | |
| 30 mM | 0.1772 mL | 0.8859 mL | 1.7718 mL | 4.4296 mL | |
| 40 mM | 0.1329 mL | 0.6644 mL | 1.3289 mL | 3.3222 mL | |
| 50 mM | 0.1063 mL | 0.5315 mL | 1.0631 mL | 2.6577 mL | |
| 60 mM | 0.0886 mL | 0.4430 mL | 0.8859 mL | 2.2148 mL | |
| 80 mM | 0.0664 mL | 0.3322 mL | 0.6644 mL | 1.6611 mL | |
| 100 mM | 0.0532 mL | 0.2658 mL | 0.5315 mL | 1.3289 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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