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Cat. No.: HY-157078

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Eg5-IN-2

Eg5-IN-2 (Compound Scaffold B (4)) is an Eg5 inhibitor (IC₅₀: < 0.5 nM). Eg5-IN-2 can be used as an ADC payload for synthesis of ADCs.

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CAS No.: 1629735-05-2
화학식: C₃₁H₃₈F₃N₅O₃
분자량:585.66

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Eg5-IN-2 Chemical Structure

CAS No.: 1629735-05-2

사이즈

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Use of MCE Products

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Biological Activity

제품 설명

Eg5-IN-2 (Compound Scaffold B (4)) is an Eg5 inhibitor (IC₅₀: < 0.5 nM). Eg5-IN-2 can be used as an ADC payload for synthesis of ADCs^[1].

All ADC Payloads Isoforms :

Chemical Information

CAS No. 1629735-05-2
분자량 585.66
화학식 C₃₁H₃₈F₃N₅O₃
SMILES

CNC(CC([C@H](C1=NC(C2=CC(F)=CC=C2F)=CN1CC3=CC=CC=C3)N(C[C@H]4[C@H](CNC4)F)C([C@@H](O)C)=O)(C)C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Karpov AS, et al. Discovery of Potent and Selective Antibody-Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization. ACS Med Chem Lett. 2019 Dec 3;10(12):1674-1679. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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Eg5-IN-2

All ADC Payloads Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Eg5-IN-2 Related Classifications

HY-157078 Related Classifications