EGFR-IN-81
EGFR-IN-81 (Compound 10i) is an EGFR inhibitor. EGFR-IN-81 inhibits EGFR WT and L858R/T790M with IC50s 4.38 nM and 5.69 nM. EGFR-IN-81 has cytotoxic activity against MCF-7 and HCT116 cells with of 2.07 μM and 6.72 μM respectively.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2968419-65-8
- 화학식: C28H24F3N5O4
- 분자량:551.52
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Chemical Information
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CAS No. 2968419-65-8
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분자량 551.52
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화학식 C28H24F3N5O4
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SMILES
FC(F)(F)C1=CC=C(NC(C2=CC=C(N(CCC3=CC=C(O)C=C3)C(NC4C(NC(CC4)=O)=O)=N5)C5=C2)=O)C=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)