Glycerol-d5
Based on 1 Customer Validation
Glycerol-d5 is the deuterium labeled Glycerol. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.06%
- CAS No.: 62502-71-0
- 화학식: C3H3D5O3
- 분자량:97.12
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보관:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 62502-71-0
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Unlabeled Cas 56-81-5
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Appearance Liquid (Density: 1.331 g/cm3)
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분자량 97.12
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화학식 C3H3D5O3
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Color Colorless to light yellow
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SMILES
OC([2H])([2H])C(O)([2H])C([2H])([2H])O
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Synonyms
Trihydroxypropane-d5
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (1029.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 100 mg/mL (1029.65 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Pennings S, et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72. [Content Brief]
[3]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun18(3):213-9. [Content Brief]
[4]. Huang ZH, et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20406(3):453-60. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 10.2965 mL | 51.4827 mL | 102.9654 mL | 257.4135 mL |
| 5 mM | 2.0593 mL | 10.2965 mL | 20.5931 mL | 51.4827 mL | |
| 10 mM | 1.0297 mL | 5.1483 mL | 10.2965 mL | 25.7414 mL | |
| 15 mM | 0.6864 mL | 3.4322 mL | 6.8644 mL | 17.1609 mL | |
| 20 mM | 0.5148 mL | 2.5741 mL | 5.1483 mL | 12.8707 mL | |
| 25 mM | 0.4119 mL | 2.0593 mL | 4.1186 mL | 10.2965 mL | |
| 30 mM | 0.3432 mL | 1.7161 mL | 3.4322 mL | 8.5805 mL | |
| 40 mM | 0.2574 mL | 1.2871 mL | 2.5741 mL | 6.4353 mL | |
| 50 mM | 0.2059 mL | 1.0297 mL | 2.0593 mL | 5.1483 mL | |
| 60 mM | 0.1716 mL | 0.8580 mL | 1.7161 mL | 4.2902 mL | |
| 80 mM | 0.1287 mL | 0.6435 mL | 1.2871 mL | 3.2177 mL | |
| 100 mM | 0.1030 mL | 0.5148 mL | 1.0297 mL | 2.5741 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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