Hydroxydihydrobovolide
Hydroxydihydrobovolide is a α-β-unsaturatedγ-lactone found in Portulaca oleracea L.. Hydroxydihydrobovolide shows cytotoxicity against cancer cells and shows anti-HIV-1 activity (IC50 = 122.7 μM). Hydroxydihydrobovolide can be used for the researches of neuroblastoma and HIV-1 infection.
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- CAS No.: 1403940-81-7
- 화학식: C11H18O3
- 분자량:198.26
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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HIV-1 122.7 μM (IC50) |
Hydroxydihydrobovolide (Compound HDB) (0.01-50 μM; 48 h) has significant cytotoxicity on SH-SY5Y cells at 50 μM[1].
Hydroxydihydrobovolide inhibits HIV-1 replication with an IC50 of 122.7 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SH-SY5Y human neuroblastoma cells
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Concentration:0.01, 0.1, 1, 10, 50 μM
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Incubation Time:48 h
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Result:Did not cause a statistically significant decrease in SH-SY5Y cell viability at 0.01-10 μM.
Significantly inhibited SH-SY5Y cell growth at 50 μM.
Chemical Information
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CAS No. 1403940-81-7
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분자량 198.26
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화학식 C11H18O3
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SMILES
CCCCC[C@]1(C(C)=C(C(O1)=O)C)O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hydroxydihydrobovolide Related Classifications
HY-N16821 Related Classifications
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