Ixazomib-13C2,15N
Ixazomib-13C2,15N is 13C and 15N labeled Ixazomib. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C1213C2H19BCl2N15NO4
- 분자량:364.01
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 1072833-77-2
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분자량 364.01
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화학식 C1213C2H19BCl2N15NO4
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SMILES
ClC1=CC(C([15N]([13C]([H])([13C](N[C@H](B(O)O)CC(C)C)=O)[H])[H])=O)=C(C=C1)Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Friedman JR, et al. Anticancer Activity of Natural and Synthetic Capsaicin Analogs. J Pharmacol Exp Ther. 2018 Mar;364(3):462-473. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)