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Cat. No.: HY-176870

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KRAS-IN-42

KRAS-IN-42 (Compound Z1063) is a covalent KRAS^G12D mutants inhibitor. KRAS-IN-42 is promising for research of KRAS^G12D-mutant cancers (e.g., non-small cell lung cancer, colorectal cancer).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3033641-67-4
화학식: C₃₆H₃₃F₄N₇O₂
분자량:671.69

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (278 KB)

KRAS-IN-42 Chemical Structure

CAS No.: 3033641-67-4

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

KRAS-IN-42 (Compound Z1063) is a covalent KRAS^G12D mutants inhibitor. KRAS-IN-42 is promising for research of KRAS^G12D-mutant cancers (e.g., non-small cell lung cancer, colorectal cancer)^[1].

IC₅₀ & Target

KRas G12D

All Ras Isoforms :

Chemical Information

CAS No. 3033641-67-4
분자량 671.69
화학식 C₃₆H₃₃F₄N₇O₂
SMILES

FC1=C(C2=CC(N)=CC3=C2C(C#C)=C(F)C=C3)N=C4C5=C1N=C(N=C5N(C[C@]6([H])N[C@@]7([H])CC6)[C@]7([H])[C@H](C)O4)OC[C@@]89N(CCC9)CC/C8=C(F)/F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jiang T, et al. Pyrimidine-fused ring compound, and preparation method therefor and use thereof. WO2024061370A1. 2024-03-28.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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KRAS-IN-42

All Ras Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

KRAS-IN-42 Related Classifications

HY-176870 Related Classifications