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Cat. No.: HY-133944

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Nitrosulfathiazole

(Synonyms: Nisulfazole; p-Nitrosulfathiazole)

Nitrosulfathiazole (Nisulfazole; p-Nitrosulfathiazole) is a sulfonamide antibacterial agent and also a key chemical intermediate for the hematotoxicity of Chloramphenicol (HY-B0239). Nitrosulfathiazole induces DNA helix instability, strand breakage and aplastic anemia. Nitrosulfathiazole can be used in research related to bacterial infections and aplastic anemia.

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CAS No.: 473-42-7
화학식: C₉H₇N₃O₄S₂
분자량:285.30

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Nitrosulfathiazole Chemical Structure

CAS No.: 473-42-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
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Bioz

Biological Activity

제품 설명

All DNA/RNA Synthesis Isoforms :

In Vitro

Nitrosulfathiazole mediates chloramphenicol-induced hematotoxicity by inhibiting DNA synthesis, causing helix destabilization, and inducing strand breakage in bone marrow stem cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 473-42-7
분자량 285.30
화학식 C₉H₇N₃O₄S₂
SMILES

O=S(C1=CC=C([N+]([O-])=O)C=C1)(NC2=NC=CS2)=O
Synonyms

Nisulfazole; p-Nitrosulfathiazole
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Shukla, P., & Singh, R. K. (2013). Effect of oral administration of chloramphenicol on hematological profile of male charles foster rats. Global journal of medical research pharma, drug discovery, toxicology and medicine, 13.

[2]. Holt D, et al. Chloramphenicol toxicity. Adverse Drug React Toxicol Rev. 1993 Summer;12(2):83-95. PMID: 8357947.
[Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

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Nitrosulfathiazole

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Nitrosulfathiazole Related Classifications

HY-133944 Related Classifications