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Cat. No.: HY-155049

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NMDA receptor antagonist 6

NMDA receptor antagonist 6 (compound 13b) is an antagonist of NMDA receptor, targeting to the glycine binding site. NMDA receptor antagonist 6 shows cytoneuroprotective potency, and protects PC12 cells against NMDA-induced injury and cell apoptosis.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₅H₂₃NO₂
분자량:369.46

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

NMDA receptor antagonist 6 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
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Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

NMDA receptor

All iGluR Isoforms :

Chemical Information

분자량 369.46
화학식 C₂₅H₂₃NO₂
SMILES

O=C1N2CC3=CC=CC=C3CC2C(C4=CC(OCC5=CC=CC=C5)=CC=C4)C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yang L, et al. Design, synthesis and evaluation of novel 1-phenyl-pyrrolo [1, 2-b] isoquinolin-3-one derivatives as antagonists for the glycine binding site of the NMDA receptor[J]. European Journal of Medicinal Chemistry, 2023: 115624.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
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NMDA receptor antagonist 6

All iGluR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

NMDA receptor antagonist 6 Related Classifications

HY-155049 Related Classifications