O-allylvanillin
Based on 1 Customer Validation
O-allylvanillin is O-allylchalcone derivative with anti-cancer effects. O-allylvanillin inhibits THP-1, HL60, Hep-G2, MCF-7 cells growth with IC50 values of 74.76 μM, 63.52 μM, 90.99 μM, and 90.11 μM, respectively.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.41%
- CAS No.: 22280-95-1
- 화학식: C11H12O3
- 분자량:192.21
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보관:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| ADR5000 cell line | IC50 |
3.48 μM
Compound: 1a
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Cytotoxicity against human CEM/ADR5000 cells assessed as reduction in cell viability after 72 hrs by RRA assay
Cytotoxicity against human CEM/ADR5000 cells assessed as reduction in cell viability after 72 hrs by RRA assay
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[PMID: 33508467] |
| CCRF-CEM | IC50 |
14.04 μM
Compound: 1a
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Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by RRA assay
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by RRA assay
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[PMID: 33508467] |
| HCT-116 | IC50 |
5.77 μM
Compound: 1a
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Cytotoxicity against human HCT-116 p53+/+ cells assessed as reduction in cell viability after 72 hrs by RRA assay
Cytotoxicity against human HCT-116 p53+/+ cells assessed as reduction in cell viability after 72 hrs by RRA assay
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[PMID: 33508467] |
| HCT-116 | IC50 |
8.02 μM
Compound: 1a
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Cytotoxicity against human HCT-116 p53-/- cells assessed as reduction in cell viability after 72 hrs by RRA assay
Cytotoxicity against human HCT-116 p53-/- cells assessed as reduction in cell viability after 72 hrs by RRA assay
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[PMID: 33508467] |
| HepG2 | IC50 |
10.46 μM
Compound: 1a
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by RRA assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by RRA assay
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[PMID: 33508467] |
| MDA-MB-231 | IC50 |
14.99 μM
Compound: 1a
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Cytotoxicity against human MDA-MB-231 pcDNA cells assessed as reduction in cell viability after 72 hrs by RRA assay
Cytotoxicity against human MDA-MB-231 pcDNA cells assessed as reduction in cell viability after 72 hrs by RRA assay
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[PMID: 33508467] |
| U-87MG ATCC | IC50 |
7.5 μM
Compound: 1a
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Cytotoxicity against human U87 cells assessed as reduction in cell viability after 72 hrs by RRA assay
Cytotoxicity against human U87 cells assessed as reduction in cell viability after 72 hrs by RRA assay
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[PMID: 33508467] |
Chemical Information
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CAS No. 22280-95-1
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Appearance Liquid (Density: 1.084±0.06 g/cm3)
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분자량 192.21
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화학식 C11H12O3
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Color Colorless to light yellow
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SMILES
O=CC1=CC=C(OCC=C)C(OC)=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (520.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.2025 mL | 26.0127 mL | 52.0253 mL | 130.0634 mL |
| 5 mM | 1.0405 mL | 5.2025 mL | 10.4051 mL | 26.0127 mL | |
| 10 mM | 0.5203 mL | 2.6013 mL | 5.2025 mL | 13.0063 mL | |
| 15 mM | 0.3468 mL | 1.7342 mL | 3.4684 mL | 8.6709 mL | |
| 20 mM | 0.2601 mL | 1.3006 mL | 2.6013 mL | 6.5032 mL | |
| 25 mM | 0.2081 mL | 1.0405 mL | 2.0810 mL | 5.2025 mL | |
| 30 mM | 0.1734 mL | 0.8671 mL | 1.7342 mL | 4.3354 mL | |
| 40 mM | 0.1301 mL | 0.6503 mL | 1.3006 mL | 3.2516 mL | |
| 50 mM | 0.1041 mL | 0.5203 mL | 1.0405 mL | 2.6013 mL | |
| 60 mM | 0.0867 mL | 0.4335 mL | 0.8671 mL | 2.1677 mL | |
| 80 mM | 0.0650 mL | 0.3252 mL | 0.6503 mL | 1.6258 mL | |
| 100 mM | 0.0520 mL | 0.2601 mL | 0.5203 mL | 1.3006 mL |
O-allylvanillin Related Classifications
HY-W080443 Related Classifications
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