Prometryn-d14
Based on 1 Customer Validation
Prometryn-d14 is the deuterium labeled Prometryn. Prometryn is a triazine herbicide. Prometryn induces apoptosis and cell cycle arrest. Prometryn induces oxidative stress, DNA damage and autophagy-related gene expression, and non-specific immunity gene expression. Prometryn can be used for the research of herbicide, hepatopancreas injury, and intestinal stress and intestinal barrier dysfunction.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.89%
- CAS No.: 1202864-57-0
- 화학식: C10H5D14N5S
- 분자량:255.44
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보관:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1202864-57-0
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Unlabeled Cas 7287-19-6
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Appearance Solid
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분자량 255.44
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화학식 C10H5D14N5S
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Color White to off-white
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SMILES
[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])NC1=NC(SC)=NC(NC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=N1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
순도&문서
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Data Sheet (272 KB)
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SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
- Norwegian - NO (537 KB)
- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Korean - KR (537 KB)
- Portuguese - PT (537 KB)
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Handling Instructions (2659 KB)
References
[1]. Liu Q, et al. Prometryn induces apoptotic cell death through cell cycle arrest and oxidative DNA damage. Toxicol Res (Camb). 2019;8(6):833-841. Published 2019 Jul 26. [Content Brief]
[2]. Huang P, et al. Effects of prometryn on oxidative stress, immune response and apoptosis in the hepatopancreas of Eriocheir sinensis (Crustacea: Decapoda). Ecotoxicol Environ Saf. Published online June 23, 2023. [Content Brief]
[3]. Huang P, et al. Prometryn exposure disrupts the intestinal health of Eriocheir sinensis: Physiological responses and underlying mechanism. Comp Biochem Physiol C Toxicol Pharmacol. 2024;277:109820. [Content Brief]
[4]. Min N, et al. Developmental toxicity of prometryn induces mitochondrial dysfunction, oxidative stress, and failure of organogenesis in zebrafish (Danio rerio). J Hazard Mater. 2023;443(Pt A):130202. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)