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Cat. No.: HY-186170B

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(R,S)-MDMA

(R,S)-MDMA acts as a partial agonist of 5-HT2A, 5-HT2B and 5-HT2C receptors. (R,S)-MDMA belongs to psychoactive substances. (R,S)-MDMA exhibits antidepressant activity. (R,S)-MDMA can be used for research on mental disorders such as post-traumatic stress disorder and depression.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 859811-50-0
화학식: C₁₂H₁₆O₂
분자량:192.25

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

(R,S)-MDMA Chemical Structure

CAS No.: 859811-50-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

5-HT_2B Receptor

52.2 nM (Kd)

5-HT_2C Receptor

158 nM (EC₅₀)

5-HT_2A Receptor

249 nM (EC₅₀)

All 5-HT Receptor Isoforms :

In Vitro

(R,S)-MDMA (55 min) acts as a partial agonist of 5-HT2A, 5-HT2B, and 5-HT2C receptors in HEK293T cells, with EC₅₀ values of 249 nM, 52.2 nM, and 158 nM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

(R,S)-MDMA (7.5 mg/kg; intraperitoneal injection; single administration) enhances sociability in C57BL/6J mice in the three-chamber social interaction test^[1].
Administration of (R,S)-MDMA (7.5 mg/kg; i.p.) during training induces significant social conditioned place preference in C57BL/6J mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

C57BL/6J mice (9-13 weeks old)^[1]
Dosage:

7.5 mg/kg
Administration:

i.p.; single dose
Result:

Increased social interaction compared to vehicle controls over the 25-min exploration period.
Showed the largest difference in prosocial behavior compared to vehicle during the final 10 min of the 30-min assay.

Chemical Information

CAS No. 859811-50-0
분자량 192.25
화학식 C₁₂H₁₆O₂
SMILES

CC(CC1=CC2=C(C=C1)OCO2)CC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Vargas MV, et al. R-MDDMA is a Safer Analogue of MDMA with Therapeutic Potential. ACS Chem Neurosci. Published online April 20, 2026. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
순도&문서
References

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(R,S)-MDMA

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

(R,S)-MDMA Related Classifications

HY-186170B Related Classifications