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Cat. No.: HY-145023

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RET-IN-5

RET-IN-5 is a potent RET (rearranged during transfection) inhibitor with an IC₅₀s of 0.4 nM and 135.1 nM for RET and VEGFR2, respectively (WO2021213476A1, compound 18).

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CAS No.: 2725770-20-5
화학식: C₂₉H₂₆FN₉O
분자량:535.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

RET-IN-5 Chemical Structure

CAS No.: 2725770-20-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

RET-IN-5 is a potent RET (rearranged during transfection) inhibitor with an IC₅₀s of 0.4 nM and 135.1 nM for RET and VEGFR2, respectively (WO2021213476A1, compound 18)^[1].

Chemical Information

CAS No. 2725770-20-5
분자량 535.57
화학식 C₂₉H₂₆FN₉O
SMILES

N#CC1=C2C(C3=CN=C(N(C)[C@H](C4=CN=C(N5C=C(C=N5)F)C=C4)C)C=C3)=CC(OCC(C)(C)C#N)=CN2N=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pyrazolo[1,5-a]pyridine derivative, preparation method therefor, and composition and use thereof. WO2021213476A1.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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