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Cat. No.: HY-111977R

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ZEN-3219 (Standard)

ZEN-3219 (Standard) is the analytical standard of ZEN-3219 (HY-111977). This product is intended for research and analytical applications. ZEN-3219 is a BET inhibitor with IC₅₀s of 0.48, 0.16 and 0.47 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3219 can be used to form PROTACs to induce degradation of BRD4.

For research use only. We do not sell to patients.

CAS No.: 1952264-34-4
Formula: C₁₉H₁₈N₂O₃
Molecular Weight:322.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ZEN-3219 (Standard) Chemical Structure

CAS No.: 1952264-34-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1952264-34-4
Molecular Weight 322.36
Formula C₁₉H₁₈N₂O₃
SMILES

O=C(C=CC(C1=C(C)ON=C1C)=C2)N2CC3=CC=C(C4OC4)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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