1952264-34-4
1952264-34-4
Chemical Structure
ZEN-3219
- CAS No.: 1952264-34-4
- Formula:C19H18N2O3
- Molecular Weight:322.36
IUPAC Name: 5-(3,5-dimethylisoxazol-4-yl)-1-(4-(oxiran-2-yl)benzyl)pyridin-2(1H)-one
InChIKey: IELJHNIVCXDKQD-UHFFFAOYSA-N
SMILES: O=C(C=CC(C1=C(C)ON=C1C)=C2)N2CC3=CC=C(C4OC4)C=C3
Biological Activity: ZEN-3219 is a BET inhibitor with IC50s of 0.48, 0.16 and 0.47 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3219 can be used to form PROTACs to induce degradation of BRD4[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ZEN-3219 | 99.75% | ZEN-3219 is a BET inhibitor with IC50s of 0.48, 0.16 and 0.47 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively. ZEN-3219 can be used to form PROTACs to induce degradation of BRD4. | ||||||||||||||||||||
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References
Keywords
