27 Results for "

cd40-ligand

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "cd40-ligand" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P72907
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; TRAP; cd154; scd40L; TNFSF5
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2
2 Cited Publications
Cat. No.: HY-P72908
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; TRAP; cd154; scd40L; TNFSF5
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Cat. No.: HY-P990083
CAS No.: 2628092-47-5
Synonyms: AT-1501

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Tegoprubart (AT-1501) is a CD40 ligand inhibitor (EC50=100 ng/mL) and immunosuppressant that selectively inhibits the CD40 ligand, a co-stimulatory molecule involved in T cell activation. Tegoprubart suppresses immune rejection, prevents rejection in animal transplantation models, and reduces cell-mediated and antibody-mediated immune responses to create a more immunotolerant environment. Tegoprubart preserves renal function when combined with Mycophenolate (HY-B0421) and Corticosteroids, and maintains graft function in preclinical studies. Tegoprubart is applicable to research related to kidney transplantation and kidney transplant rejection .
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Cat. No.: HY-P99625
CAS No.: 2515463-86-0
Synonyms: SAR441344; INX-021

Target:  

TNF Receptor

Frexalimab (SAR441344) is a second-generation monoclonal antibody targeting the CD40 ligand (CD40L) with a good safety profile. Frexalimab inhibits the binding between CD40 and CD40L to modulate immune response. Frexalimab is likely to help prevent the process of β-cell destruction. Frexalimab is proming for multiple sclerosis, lupus erythematosus, Sj gren’s syndrome and type I diabetes research .
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Cat. No.: HY-P99325
CAS No.: 252662-47-8
Synonyms: IDEC-131; Anti-Human cd40 ligand Recombinant Antibody

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Toralizumab (IDEC-131) is a humanized monoclonal antibody (mAb) against CD40L (CD154) comprised of human gamma 1 heavy chains and human kappa light chains. Toralizumab binds specifically to human CD40L on T cells, thereby preventing CD40 signaling. Toralizumab is an immunosuppressive agent. Toralizumab can lead to increased thrombosis. Toralizumab can be studied in research for diseases such as multiple sclerosis, systemic lupus erythematosus (SLE), and Crohn’s disease .
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Cat. No.: HY-P991557

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

ABI793 is a human IgG1 anti-human CD154 (CD40 ligand) monoclonal antibody. ABI793 inhibits immune response by blocking the CD154-CD40 (IC50 = 75 nM) signaling pathway. ABI793 effectively prevents kidney transplant rejection. ABI793 can be used for research on immunological rejection .
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Cat. No.: HY-P72122
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: cd40LG; cd40L; TNFSF5cd40 ligand; cd40-L; Tumor necrosis factor ligand superfamily member 5; cd antigen cd154; cd40 ligand; membrane form; cd40 ligand; soluble form; scd40L;
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Cat. No.: HY-P72121
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: cd40LG; cd40L; TNFSF5cd40 ligand; cd40-L; Tumor necrosis factor ligand superfamily member 5; cd antigen cd154; cd40 ligand; membrane form; cd40 ligand; soluble form; scd40L;
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Cat. No.: HY-P72907AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: soluble cd40 ligand; cd40 ligand; cd40-L; TRAP; cd154; scd40L; TNFSF5
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Cat. No.: HY-P705466
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; TRAP; cd154; scd40L; TNFSF5
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Cat. No.: HY-P78934
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; TRAP; cd154; scd40L; TNFSF5
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Cat. No.: HY-P75407
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; TRAP; cd154; scd40L; TNFSF5
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Cat. No.: HY-P74294
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; TRAP; cd154; scd40L; TNFSF5
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Rat
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Cat. No.: HY-P75406
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; TRAP; cd154; scd40L; TNFSF5
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Cat. No.: HY-P75405
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; TRAP; cd154; scd40L; TNFSF5
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Cat. No.: HY-P70609G
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; TRAP; cd154; TNFSF5
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Cat. No.: HY-P71910
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: cd 40L; cd154; cd40 antigen ligand; cd40 ligand; cd40 ligand; soluble form; cd40-L; cd40L; cd40L_HUMAN; cd40LG; gp39; hcd40L; HIGM1; IGM; IMD3; T B cell activating molecule; T BAM; T-cell antigen Gp39; TNF-related activation protein; TNFSF5; TrAP; Tumor necrosis factor ligand; superfamily member 5; Tumor necrosis factor ligand superfamily member 5
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Cat. No.: HY-P990083A
CAS No.: 2628092-47-5
Synonyms: AT-1501 (powder)

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Tegoprubart (powder) (AT-1501 (powder)) is a CD40 ligand inhibitor (EC50=100 ng/mL) and immunosuppressant that selectively inhibits the CD40 ligand, a co-stimulatory molecule involved in T cell activation. Tegoprubart (powder) suppresses immune rejection, prevents rejection in animal transplantation models, and reduces cell-mediated and antibody-mediated immune responses to create a more immunotolerant environment. Tegoprubart (powder) preserves renal function when combined with Mycophenolate (HY-B0421) and Corticosteroids, and maintains graft function in preclinical studies. Tegoprubart (powder) is applicable to research related to kidney transplantation and kidney transplant rejection .
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Cat. No.: HY-P70609
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40-L; T-Cell Antigen Gp39; TNF-Related Activation Protein; TRAP; Tumor Necrosis Factor ligand Superfamily Member 5; cd154; cd40LG; cd40L; TNFSF5; TRAP
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Cat. No.: HY-P70808
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: cd40 ligand; cd40LG; HIGM1; T-B cell-activating molecule; T-BAM; TNFSF5; tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor ligand superfamily member 5
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