28 Results for "

il-4r-alpha

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "il-4r-alpha" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-P9926
CAS No.: 1190264-60-8
Synonyms: REGN-668; SAR-231893

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis .
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1 Cited Publications
Cat. No.: HY-P99025
CAS No.: 953400-68-5
Synonyms: TNX-650; MilR1444A; RG3637

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .
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1 Cited Publications
Cat. No.: HY-P7220
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuil-4r; il4r; il-4rA; CD124
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Cat. No.: HY-P990093
CAS No.: 2734715-10-5
Synonyms: CM310

Research Areas:  

Inflammation/Immunology

Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα (KD values of 0.25 nM, 1.50 nM, and 2.75 nM for human, cynomolgus monkey, and rat IL-4Rα, respectively). Stapokibart effectively blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit IL-4Rα. Stapokibart reduces IL-4 and IL-13 mRNA, inhibits CD23 upregulation, and inhibits IL-4 and IL-13-induced STAT6 activation. Stapokibart improves inflammation (airway inflammation, rhinitis, dermatitis) .
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Cat. No.: HY-P990090
CAS No.: 2648260-80-2
Synonyms: CBP-201

Research Areas:  

Inflammation/Immunology

Rademikibart (CBP-201) is a human monoclonal antibody targeting IL-4Rα and IL-4Rα inhibitor with a KD of 20.7 pM when binding to human IL-4Rα epitopes . Rademikibart does not bind to IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation and thymus activation regulated chemokine (TRAC) production. Rademikibart can be used for the research of atopic dermatitis and asthma .
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Cat. No.: HY-P99724
CAS No.: 2428381-56-8
Synonyms: AK120

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Manfidokimab (AK120) is an anti-interleukin 4 receptor alpha (IL-4Rα) IgG4 monoclonal antibody .
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Cat. No.: HY-P991515

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

TQH-2722 is a humanized IgG4 anti-IL-4Rα monoclonal antibody. TQH-2722 targets the IL-4Rα receptor in humans, effectively disrupting the interaction between IL-4Rα and the downstream cytokines IL-4 and IL-13, thereby inhibiting inflammatory response. TQH-2722 can be used for the study of atopic dermatitis (AD) and chronic rhinosinusitis with nasal polyps (CRSwNP) .
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Cat. No.: HY-P991283

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

AMG 317 is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002). AMG 317 can be used in research related to asthma .
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Cat. No.: HY-P77010
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4 receptor subunit alpha; il4r alpha; il4r; CD124
Species:  
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Cat. No.: HY-P77009
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4 receptor subunit alpha; il4r alpha; il4r; CD124
Species:  
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Cat. No.: HY-P74801
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4 receptor subunit alpha; il4r alpha; il4r
Species:  
Rat
Source:  
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Cat. No.: HY-P991285

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

MEDI-9314 is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. MEDI-9314 can be used in research related to skin allergy .
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Cat. No.: HY-P703952
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD124; il-4 R alpha; il-4r subunit alpha; il4r; il-4ra; il4rACD124
Species:  
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Cat. No.: HY-P700001
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4 receptor subunit alpha; il-4 receptor subunit alpha; il-4r subunit alpha; il-4r-alpha; il-4rA; CD124
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Cat. No.: HY-P70712
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4 receptor subunit alpha; il-4 receptor subunit alpha; il-4r subunit alpha; il-4r-alpha; il-4rA; CD124; il-4-binding protein; il4-BP; il4r; il4rA
Species:  
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Cat. No.: HY-P70710
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4 receptor subunit alpha; il-4 receptor subunit alpha; il-4r subunit alpha; il-4r-alpha; il-4rA; CD124; il-4-binding protein; il4-BP; il4r; il4rA
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Cat. No.: HY-P73217
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4 receptor subunit alpha; il-4r-alpha; il-4rA; CD124; il4-BP; il4r
Species:  
Rat
Source:  
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Cat. No.: HY-P70325
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuInterleukin-4 receptor subunit alpha/il-4 RA, mFc; Interleukin-4 receptor subunit alpha; il-4 receptor subunit alpha; il-4r subunit alpha; il-4r-alpha; il-4rA; CD124; il-4-binding protein; il4-BP; il4r; il4rA
Species:  
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Cat. No.: HY-P72541
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-4 receptor subunit alpha; il-4rA; il-4r-alpha; CD124; il4-BP
Species:  
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Cat. No.: HY-P992033

Target:  

Interleukin Related

Research Areas:  

Cancer

Anti-Mouse IL-4Rα Antibody (REGN1103) is a mouse homologous antibody targeting IL-4Rα, as well as an inhibitor of IL-4 signaling. Anti-Mouse IL-4Rα Antibody (REGN1103) can be used in studies related to alveolar rhabdomyosarcoma .
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