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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
il-6r-alpha
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "il-6r-alpha" in MCE Product Catalog:
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1 Cited Publications
Cat. No.: HY-P990211
Target:
Research Areas:
Cat. No.: HY-P705048
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-6 receptor subunit alpha; il-6r subunit alpha; il-6r-alpha; il-6r 1; Membrane glycoprotein 80; gp80; CD126
Cat. No.: HY-P704718
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-6 receptor subunit alpha; il-6r-alpha; il-6r 1; sil6r; CD126
Cat. No.: HY-P73225
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-6 receptor subunit alpha; il-6r-alpha; il-6r 1; gp80; CD126
Species:
Source:
Cat. No.: HY-P705639
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-6 receptor subunit alpha; L-6r subunit alpha; il-6r-alpha; il-6r 1; Membrane glycoprotein 80; gp80; CD126; il-6/il-6r alpha Chimera Protein
Cat. No.: HY-P7377
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuil-6 Receptor α; gp80; CD126
Species:
Source:
Cat. No.: HY-182273
CAS No.: 3106606-59-8
Target:
Research Areas:
DM243 is an EPAC1 activator and STAT3 modulator with an pIC50 of 4.769 for EPAC1. DM243 increases GTP-bound Rap1 levels in EPAC1-expressing cells. DM243 reduces IL-6/IL-6Rα-evoked STAT3 phosphorylation in endothelial cells. DM243 suppresses TGF-β1-induced fibroblast-to-myofibroblast transition, reducing α-smooth muscle actin and Collagen I levels in lung fibroblasts. DM243 exhibits minimal cytotoxicity in normal human lung fibroblasts .
Cat. No.: HY-182274
CAS No.: 3106606-60-1
Target:
Research Areas:
DM245 is an EPAC1 activator and STAT3 phosphorylation inhibitor with a target pIC50 of 4.801. DM245 activates EPAC1 to increase Rap1-GTP levels, with no activation of EPAC2 or PKA. DM245 reduces IL-6/IL-6Rα-evoked STAT3 phosphorylation in endothelial cells. DM245 suppresses TGF-β1-induced fibroblast-to-myofibroblast transition, reducing αSMA and Collagen I levels. DM245 exhibits minimal cytotoxicity in normal human lung fibroblasts, with negligible loss of intact nuclei after 72 h exposure .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
