Qingdainone
Based on 1 publication(s) in Google Scholar
Qingdainone is a quinazoline alkaloid and also a TMPRSS2 inhibitor. Qingdainone can be isolated from Strobilanthes cusia. Qingdainone exhibits anti-tumor and anti-inflammatory activities. Qingdainone can be used in studies related to chronic myeloid leukemia.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 97457-31-3
- Formule: C23H13N3O2
- Masse moléculaire:363.37
-
Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Qingdainone
More
Activité biologique
Qingdainone binds tightly to homology-modeled human TMPRSS2 with a docked binding energy of -9.6 kcal/mol, forming specific hydrogen bonds and hydrophobic interactions with key protein residues[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 97457-31-3
-
Appearance Solid
-
Masse moléculaire 363.37
-
Formule C23H13N3O2
-
Color Brown to black
-
SMILES
O=C1C2=CC=CC=C2N/C1=C3C4=CC=CC=C4N5C\3=NC6=CC=CC=C6C5=O
-
Structure Classification
-
Initial Source
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
J Ethnopharmacol
Mechanism of action of Pulsatilla chinensis (Bunge) Regel compounds in hepatocellular carcinoma (HCC) treatment: An integrated analysis combining network pharmacology, molecular docking, molecular dynamics simulations and luciferase reporter gene assay. [Abstract]2025 Aug 29:352:120176. PMID: 40543694
Pureté et documentation
-
Fiche technique (278 KB)
-
SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
-
Instruction de manipulation (2659 KB)
Références
[1]. Vivek-Ananth RP, et al. In Silico Identification of Potential Natural Product Inhibitors of Human Proteases Key to SARS-CoV-2 Infection. Molecules. 2020 Aug 22;25(17):3822. [Content Brief]
[2]. Li H, et al. Deciphering Key Pharmacological Pathways of Qingdai Acting on Chronic Myeloid Leukemia Using a Network Pharmacology-Based Strategy. Med Sci Monit. 2018 Aug 15;24:5668-5688. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Qingdainone Related Classifications
HY-W749874 Related Classifications
Powered by Bioz