97457-31-3
97457-31-3
Chemical Structure
Qingdainone
- CAS No.: 97457-31-3
- Formula:C23H13N3O2
- Molecular Weight:363.37
IUPAC Name: (E)-6-(3-oxoindolin-2-ylidene)indolo[2,1-b]quinazolin-12(6H)-one
InChIKey: DXENDDMPDZMHSQ-FMQUCBEESA-N
SMILES: O=C1C2=CC=CC=C2N/C1=C3C4=CC=CC=C4N5C\3=NC6=CC=CC=C6C5=O
Biological Activity: Qingdainone is a quinazoline alkaloid and also a TMPRSS2 inhibitor. Qingdainone can be isolated from Strobilanthes cusia. Qingdainone exhibits anti-tumor and anti-inflammatory activities. Qingdainone can be used in studies related to chronic myeloid leukemia[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Qingdainone | 98.10% | Qingdainone is a quinazoline alkaloid and also a TMPRSS2 inhibitor. Qingdainone can be isolated from Strobilanthes cusia. Qingdainone exhibits anti-tumor and anti-inflammatory activities. Qingdainone can be used in studies related to chronic myeloid leukemia. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.52
HY-W338764AHR agonist 3 -
Similarity Score 0.51
HY-19805STO-609 -
Similarity Score 0.51
HY-D0457C.I. Solvent red 179 -
Similarity Score 0.50
HY-19805ASTO-609 acetate -
Similarity Score 0.49
HY-D0242Vat Red 15 -
Similarity Score 0.49
HY-148757TIM-063 -
Similarity Score 0.48
HY-11843810-Cl-BBQ -
Similarity Score 0.47
HY-D1457DND-189 -
Similarity Score 0.47
HY-N0335Indigo -
Explore the MedChemAI to find more analogs
References
- [1]. Vivek-Ananth RP, et al. In Silico Identification of Potential Natural Product Inhibitors of Human Proteases Key to SARS-CoV-2 Infection. Molecules. 2020 Aug 22;25(17):3822. [Content Brief]
- [2]. Li H, et al. Deciphering Key Pharmacological Pathways of Qingdai Acting on Chronic Myeloid Leukemia Using a Network Pharmacology-Based Strategy. Med Sci Monit. 2018 Aug 15;24:5668-5688. [Content Brief]
