1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. Quinelorane dihydrochloride

Quinelorane dihydrochloride (Synonyms: LY163502)

Cat. No.: HY-103429
Handling Instructions

Quinelorane dihydrochloride (LY163502) is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research.

For research use only. We do not sell to patients.

Quinelorane dihydrochloride Chemical Structure

Quinelorane dihydrochloride Chemical Structure

CAS No. : 97548-97-5

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Description

Quinelorane dihydrochloride (LY163502) is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research[1][2].

IC50 & Target[1][2]

D2 Receptor

 

D3 Receptor

 

In Vivo

Quinelorane dihydrochloride (LY163502; 0.003, 0.01 mg/kg; s.c.) reduces GABA efflux, with significant effects with 0.01 but not 0.003 mg/kg in male Wistar rats (300 g)[1].
Quinelorane dihydrochloride (0.032, 0.32, 3.2, 5.6 mg/kg; IP) significantly and dose-dependently increases locomotor activity in the Sprague Dawley rats. There was no main effect of sex and sex interaction[1].
Quinelorane dihydrochloride significantly decreases activity in the male and female inbred FVB/NJ, BALB/cJ, BALB/cByJ, C57BL/6J, Swiss Webster, A/J, DBA/2J, 129S1/SvImJ, and 129S6/SvEvTac mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

319.27

Formula

C₁₄H₂₄Cl₂N₄

CAS No.
Shipping

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Quinelorane dihydrochloride
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HY-103429
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