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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
136 Results for "
TNF-R
" in MedChemExpress (MCE) Product Catalog:
Products (136)
136 Results for "TNF-R" in MCE Product Catalog:
Cat. No.: HY-P705276
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF1B; TNF-R2; Prev. TNFR2; Tumor Necrosis Factor Receptor Superfamily, Member 1B; TNFBR; Tumor Necrosis Factor Receptor Superfamily, Member 1b; P75; Tumor Necrosis Factor Binding Protein 2; TNF-R-II; Tumor Necrosis Factor Beta Receptor; TNF-R75; Solub
Cat. No.: HY-11109R
CAS No.: 243984-11-4
Synonyms: TAK-242 (Standard); CLI-095 (Standard)
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Resatorvid (Standard) is the analytical standard of Resatorvid (HY-11109). This product is intended for research and analytical applications. Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases .
Cat. No.: HY-P992399
Target:
Research Areas:
Cat. No.: HY-110203R
CAS No.: 303997-35-5
Synonyms: TNF-α Antagonist III (Standard)
Target:
Research Areas:
R-7050 (Standard) is the analytical standard of R-7050 (HY-110203). This product is intended for research and analytical applications. R-7050 (TNF-α Antagonist III) is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.
Cat. No.: HY-111255AR
CAS No.: 1049741-03-8
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SPD304 dihydrochloride (Standard) is the analytical standard of SPD304 (dihydrochloride) (HY-111255A). This product is intended for research and analytical applications. SPD304 dihydrochloride is a selective TNF-α inhibitor, which promotes dissociation of TNF trimers and therefore blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 μM for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF-α .
Cat. No.: HY-111255R
CAS No.: 869998-49-2
Target:
Research Areas:
SPD304 (Standard) is the analytical standard of SPD304 (HY-111255). This product is intended for research and analytical applications. SPD304 is a selective TNF-α inhibitor, which promotes dissociation of TNF trimers and therefore blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 μM for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF-α .
Cat. No.: HY-182884
Target:
Research Areas:
TNF-α-IN-29 is an orally active and selective TNF-α inhibitor, with IC50 values of 123.0 nM against human targets, and a human Kd of 45.9 nM. TNF-α-IN-29 blocks TNF-α-TNFR1 protein-protein interactions and inhibits TNF-α-mediated inflammatory signaling pathways. TNF-α-IN-29 exhibits anti-inflammatory effects in a mouse model of collagen-induced arthritis and promotes articular cartilage repair. TNF-α-IN-29 can be used for the research of rheumatoid arthritis .
Cat. No.: HY-RS17012
Target:
Research Areas:
Tnfrsf1a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfrsf1a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70683
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
Cat. No.: HY-P75163
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
Cat. No.: HY-P75164
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
Cat. No.: HY-P78640
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
Cat. No.: HY-P78716
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
Species:
Source:
Cat. No.: HY-P73076
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
Cat. No.: HY-P75165
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
Cat. No.: HY-P76362
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
Species:
Source:
Cat. No.: HY-183516
CAS No.: 19220-35-0
Synonyms: OPG
Target:
Research Areas:
Osteoprotegerin (OPG) belongs to the tumor necrosis factor receptor (TNFR) superfamily . Osteoprotegerin blocks the RANKL-RANK interaction as well as the binding of TRAIL to its receptor. Osteoprotegerin activates NF-κB to induce the expression of ICAM-1, VCAM-1 and E-selectin, and activates the phosphorylation of ERK1/2. Osteoprotegerin regulates osteoclast activity, inhibits osteoclast maturation and formation, bone lysis and bone resorption, and increases bone mass. Osteoprotegerin regulates vascular endothelial cell function. Osteoprotegerin can be used in the research of cardio-cerebrovascular and bone-related diseases .
Cat. No.: HY-P72631
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
Cat. No.: HY-P75166
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF18; Glucocorticoid-Induced TNFR-Related Protein; TNF Receptor Superfamily Member 18; Activation-Inducible TNFR Family Receptor; AITR; Tumor Necrosis Factor Receptor Superfamily Member 18 Isoform 4; GITR; TNF Receptor Superfamily Activation-Inducible
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
