869998-49-2
869998-49-2
Chemical Structure
SPD304
- CAS No.: 869998-49-2
- Formula:C32H32F3N3O2
- Molecular Weight:547.61
IUPAC Name: 6,7-dimethyl-3-((methyl(2-(methyl((1-(3-(trifluoromethyl)phenyl)-1H-indol-3-yl)methyl)amino)ethyl)amino)methyl)-4H-chromen-4-one
InChIKey: JZNXLPPJRFFECJ-UHFFFAOYSA-N
SMILES: O=C1C(CN(C)CCN(C)CC2=CN(C3=CC=CC(C(F)(F)F)=C3)C4=C2C=CC=C4)=COC5=CC(C)=C(C)C=C15
Biological Activity: SPD304 is a selective TNF-α inhibitor, which promotes dissociation of TNF trimers and therefore blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 μM for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF-α[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SPD304 | 99.72% | SPD304 is a selective TNF-α inhibitor, which promotes dissociation of TNF trimers and therefore blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 μM for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF-α. | ||||||||||||||||||||
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SPD304 (Standard) | ≥98% | SPD304 (Standard) is the analytical standard of SPD304 (HY-111255). This product is intended for research and analytical applications. SPD304 is a selective TNF-α inhibitor, which promotes dissociation of TNF trimers and therefore blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 μM for inhibiting in vitro TNF receptor 1 (TNFR1) binding to TNF-α. | ||||||||||||||||||||
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