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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
( )-R 41400
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "( )-R 41400" in MCE Product Catalog:
30
Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
1
1 Cited Publications
Art. -Nr.: HY-B0105B
CAS. Nr.: 142128-57-2
Synonyms: (-)-Ketoconazole; (-)-Ketoconazol; (-)-R 41400
Target:
Forschungsgebiete:
Levoketoconazole ((-)-Ketoconazole) is the 2S,4R enantiomer derived from racemic Ketoconazole (HY-B0105). Levoketoconazole is a potent and orally active cortisol synthesis inhibitor. Levoketoconazole inhibits key steps in cortisol and testosterone synthesis by inhibiting CYP11B1, CYP11A1, and CYP17A1. Levoketoconazole can be used for research on endogenous Cushing’s syndrome .
Art. -Nr.: HY-B0105A
CAS. Nr.: 142128-59-4
Synonyms: (+)-Ketoconazol; (+)-R 41400
Target:
Forschungsgebiete:
(+)-Ketoconazole ((+)-R 41400) is an imidazole anti-fungal agent, a CYP3A4 inhibitor.
Art. -Nr.: HY-B0105R
CAS. Nr.: 65277-42-1
Synonyms: Ketoconazol (Standard); R 41400 (Standard)
Ketoconazole (Standard) is the analytical standard of Ketoconazole. This product is intended for research and analytical applications. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
Art. -Nr.: HY-B0105S1
CAS. Nr.: 1398065-75-2
Synonyms: Ketoconazol-d4; R 41400-d4
Art. -Nr.: HY-B0105S
CAS. Nr.: 1217706-96-1
Art. -Nr.: HY-166670S
Synonyms: Ketoconazol-13C; R 41400-13C
Art. -Nr.: HY-W422288
CAS. Nr.: 79156-75-5
Synonyms: (Rac)-Ketoconazol; (Rac)-R 41400
Target:
Forschungsgebiete:
(Rac)-Ketoconazole ((Rac)-R 41400) is an antifungal imidazole compound with oral activity. (Rac)-Ketoconazole interferes with ergosterol synthesis by inhibiting cytochrome P450-dependent 14α-sterol demethylase (CYP51), a key enzyme on the fungal cell membrane, leading to membrane dysfunction and ultimately inhibition of fungal growth and reproduction. (Rac)-Ketoconazole is indicated for studies of fungal infections .
Art. -Nr.: HY-B0105BS
CAS. Nr.: 1217766-70-5
Synonyms: (-)-Ketoconazole-d3; (-)-Ketoconazol-d3; (-)-R 41400-d3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
