142128-59-4
142128-59-4
Chemical Structure
(+)-Ketoconazole
Synonym(s): (+)-Ketoconazol; (+)-R 41400
- CAS No.: 142128-59-4
- Formula:C26H28Cl2N4O4
- Molecular Weight:531.43
IUPAC Name: 1-(4-(4-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one
InChIKey: XMAYWYJOQHXEEK-OZXSUGGESA-N
SMILES: ClC(C=C1)=CC(Cl)=C1[C@@]2(CN3C=CN=C3)OC[C@H](COC4=CC=C(N5CCN(C(C)=O)CC5)C=C4)O2
Biological Activity:
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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(+)-Ketoconazole | 99.79% | (+)-Ketoconazole ((+)-R 41400) is an imidazole anti-fungal agent, a CYP3A4 inhibitor. | ||||||||||||||||||||
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References
- Eil C. Ketoconazole binds to the human androgen receptor. Horm Metab Res. 1992 Aug;24(8):367-70. [Content Brief]
- Seif El-Din SH, et al. Effect of ketoconazole, a cytochrome P450 inhibitor, on the efficacy of quinine and halofantrine against Schistosoma mansoni in mice. Korean J Parasitol. 2013 Apr;51(2):165-75. [Content Brief]
Keywords
