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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
12-HETE
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "12-HETE" in MCE Product Catalog:
2
2 Cited Publications
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2 Cited Publications
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BW 755C is a 5-lipoxygenase (5-LO) inhibitor with an IC50 of 5 μM. BW 755C also inhibits cyclooxygenase (COX) with IC50s of 0.65 and 1.2 μg/mL against COX-1 and COX-2, respectively .
Cat. No.: HY-125122
CAS No.: 68978-04-1
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Cat. No.: HY-117044A
CAS No.: 81187-21-5
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(±)12-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 12(S)-HEPE and 12(R)-HEPE. The biological activity of (±)12-HEPE is likely mediated by one of the individual isomers, most commonly the 12(S) isomer in mammalian systems. 12-HEPE inhibits platelet aggregation with the same potency as 12-HETE, exhibiting IC50 values of 24 and 25 μM, respectively.1 These compounds are also equipotent as inhibitors of U46619-induced contraction of rat aorta (IC50s=8.6-8.8 μM).
Cat. No.: HY-185709
CAS No.: 53847-31-7
Synonyms: 1-Lyso-2-arachidonoyl-sn-glycero-3-phosphoethanolamine
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2-ARA-LysoPtdEtn (1-Lyso-2-arachidonoyl-sn-glycero-3-phosphoethanolamine) is an orally active polyunsaturated acyl lysophosphatidylethanolamine. 2-ARA-LysoPtdEtn diminishes formation of LTC4, LTB4, and 12-HETE. 2-ARA-LysoPtdEtn lowers levels of IL-1β, IL-6, TNF-α, and NO. 2-ARA-LysoPtdEtn augments IL-10 levels and upgrades formation of 15-HETE and LXA4. 2-ARA-LysoPtdEtn can be used for the research of peritonitis .
Cat. No.: HY-CE00676
Synonyms: 12-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-coenzyme A
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12-HETE-CoA (12-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-coenzyme A) is an unsaturated fatty acyl-CoA.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
