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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
3D-QSAR
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "3D-QSAR" in MCE Product Catalog:
Cat. No.: HY-150558
CAS No.: 727730-24-7
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CYP1B1-IN-2 (compound 9j) is a potent and selective CYP1B1 (cytochrome P450 1B1) inhibitor, with an IC50 of 0.52 nM .
Cat. No.: HY-178988
Antibacterial agent 299 (Compound P5) is a highly effective antibacterial agent against Xanthomonas oryzae pv. oryzae (Xoo), with an EC₅₀ value of 6.9 μg/mL. Antibacterial agent 299 integrates into bacterial membranes, disrupts membrane structure, inhibits biofilm formation, and thus exerts antibacterial effects. Antibacterial agent 299 also shows inhibitory activity against Xanthomonas oryzae pv. oryzicola (Xoc) (EC₅₀ = 32.5 ± 3.0 μg/mL), but its activity against Xanthomonas axonopodis pv. citri (Xac) is weaker. Antibacterial agent 299 demonstrated excellent control efficacy in a rice bacterial blight (BLB) model. Antibacterial agent 299 can be used for BLB research .
Cat. No.: HY-10793
CAS No.: 802536-13-6
CDK2-IN-56 (compound 39) is a pyrazoloquinazoline-3-carboxamide and CDK2/CyA inhibitor. CDK2-IN-56 can be used for the research of cancer .
Cat. No.: HY-153501
CAS No.: 1377503-70-2
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TrkA-IN-5 is a TrkA inhibitor with an IC50 value of 1.678 nM against TrkA. TrkA-IN-5 can be used in cancer research .
Cat. No.: HY-180274
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JAK1/2-IN-3 is a JAK1 and JAK2 inhibitor with IC50 values of 14.73 nM and 10.03 nM, respectively. JAK1/2-IN-3 induces G2/M cell cycle arrest, and induces intrinsic apoptosis via increased Bax and caspase 3/7 levels and reduced Bcl2 expression. JAK1/2-IN-3 can be used for the study of leukemia cancer, breast cancer and colon cancer .
Cat. No.: HY-184794
CAS No.: 67651-34-7
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2,3,4,5-Tetrachloro-4′-biphenylol is an Androgen receptor ligand with a pIC50 value of 4.79. 2,3,4,5-Tetrachloro-4′-biphenylol is an environmental chemical that exerts endocrine-disrupting activity .
Cat. No.: HY-148584
CAS No.: 2170788-98-2
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BTK-IN-21 (Compound 12) is a BTK inhibitor with an IC50 of 33 nM. BTK-IN-21 can be used for research in cancer and autoimmunity therapies .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
