CYP1B1-IN-2
CYP1B1-IN-2 (compound 9j) is a potent and selective CYP1B1 (cytochrome P450 1B1) inhibitor, with an IC50 of 0.52 nM.
For research use only. We do not sell to patients.
- CAS No.: 727730-24-7
- Formula: C20H11F3O2
- Molecular Weight:340.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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CYP1B1 0.52 nM (IC50) |
CYP1A1 16.7 nM (IC50) |
CYP1A2 94.2 nM (IC50) |
Chemical Information
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CAS No. 727730-24-7
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Molecular Weight 340.30
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Formula C20H11F3O2
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SMILES
O=C1C=C(C2=CC=CC(C(F)(F)F)=C2)OC3=C1C=CC4=CC=CC=C43
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)