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Cat. No.: HY-10793

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CDK2-IN-56

CDK2-IN-56 (compound 39) is a pyrazoloquinazoline-3-carboxamide and CDK2/CyA inhibitor. CDK2-IN-56 can be used for the research of cancer.

For research use only. We do not sell to patients.

CAS No.: 802536-13-6
Formula: C₁₈H₂₅N₇O₃S
Molecular Weight:419.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK2-IN-56 Chemical Structure

CAS No.: 802536-13-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

CDK2-IN-56 (compound 39) is a pyrazoloquinazoline-3-carboxamide and CDK2/CyA inhibitor. CDK2-IN-56 can be used for the research of cancer^[1].

IC₅₀ & Target

cdk2/cyclin A

All CDK Isoforms :

In Vitro

CDK2-IN-56 (Cpd39) potently inhibits CDK2/CyA with an actual pIC₅₀ of 8.699, and its activity is accurately predicted by both CoMFA and CoMSIA 3D-QSAR models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 802536-13-6
Molecular Weight 419.50
Formula C₁₈H₂₅N₇O₃S
SMILES

O=C(NC)C1=NN(C)C2=C1CCC3=CN=C(NC4CCN(S(C)(=O)=O)CC4)N=C32
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Lan P, et al. 3D-QSAR and docking studies on pyrazolo[4,3-h]qinazoline-3-carboxamides as cyclin-dependent kinase 2 (CDK2) inhibitors. Bioorg Med Chem Lett. 2010;20(22):6764-6772. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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