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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
AK1
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "AK1" in MCE Product Catalog:
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AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor, with an IC50 of 12.5 μM.
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HR-19011 is an eIF2α phosphorylation activator targeting heme-regulated inhibitor HRI (EIF2AK1). HR-19011 exhibits growth inhibitory activity against K562 cells with an IC50 value of 3.91 µM. HR-19011 inhibits the growth of hematologic malignancies by targeting HRI to activate the integrated stress response via the HRI-eIF2α-ATF4 axis. HR-19011 shows good safety in vivo. HR-19011 can be used for research on hematologic malignancies (leukemia) [1] .
Cat. No.: HY-RS00505
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AK1 Human Pre-designed siRNA Set A contains three designed siRNAs for AK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W587827
CAS No.: 3475-65-8
Synonyms: Thiamine triphosphate
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Thiamine triphosphoric acid ester (Thiamine triphosphate) is a neuroactive compound and a triphosphate derivative of vitamin thiamine. Thiamine triphosphoric acid ester exists in microorganisms, animal organs and plants. In E. coli, Thiamine triphosphoric acid ester is transiently produced under amino acid deficiency, while in mammalian cells, it is continuously produced at a low rate. Thiamine triphosphoric acid ester can be synthesized by two distinct enzymes (cytosolic AK1 and FoF1-ATP synthase in brain mitochondria). Thiamine triphosphoric acid ester plays a fundamental role in cellular metabolism or cellular signal transduction [1] .
Cat. No.: HY-RS23292
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Ak1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ak1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16851
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Ak1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ak1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-101465R
CAS No.: 330461-64-8
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AK-1 (Standard) is the analytical standard of AK-1 (HY-101465). This product is intended for research and analytical applications. AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor, with an IC50 of 12.5 μM.
Cat. No.: HY-174999
CAS No.: 2914873-59-7
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JAK3-IN-18 is an orally active JAK3 and TEC inhibitor, with IC50s of 0.5391 nM and 12.40 nM, respectively. JAK3-IN-18 demonstrates outstanding selectivity over AK1, AK2, and TYk2, with selectivity ratios exceeding 10,000-fold. JAK3-IN-18 demonstrates excellent therapeutic efficacy in the experimental autoimmune encephalomyelitis (EAE) mouse model. JAK3-IN-18 can be used for the study of multiple sclerosis [1].
Cat. No.: HY-RS04242
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EIF2AK1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF2AK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28519
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Eif2ak1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif2ak1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P74427
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AK1; Adk1; Adenylate Kinase 1; ADK; Adenylate Monophosphate Kinase; HTL-S-58j; Adenylate Kinase Isoenzyme 1; AK 1; ATP-AMP Transphosphorylase 1; Testis Secretory Sperm Binding Protein Li 58j; ATP:AMP Phosphotransferase; Epididymis Secretory Sperm Binding
Cat. No.: HY-P74428
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AK1; Adk1; Adenylate Kinase 1; ADK; Adenylate Monophosphate Kinase; HTL-S-58j; Adenylate Kinase Isoenzyme 1; AK 1; ATP-AMP Transphosphorylase 1; Testis Secretory Sperm Binding Protein Li 58j; ATP:AMP Phosphotransferase; Epididymis Secretory Sperm Binding
Cat. No.: HY-RS22002
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Eif2ak1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif2ak1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
