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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
AMY3
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "AMY3" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: BMS-927711; BHV-3000
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Rimegepant (BMS-927711; BHV-3000) is an orally bioavailable and blood-brain barrier permeable antagonist of CGRP and AMY1 receptors, with a pIC50 of 8.01 and a Ki of 0.027 nM for human CGRP receptors. Rimegepant antagonizes cAMP production induced by αCGRP, βCGRP and amylin at CGRP and AMY1 receptors in humans, rats and mice, as well as at rat AMY3 receptors. Rimegepant can be used in research related to migraine .
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5 Cited Publications
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MK-3207 (Hydrochloride) is a potent and orally bioavailable CGRP receptor antagonist with IC50 of 0.12 nM and Ki of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3.
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Cat. No.: HY-P10798
CAS No.: 2883634-40-8
Synonyms: LY-3841136
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Cat. No.: HY-P10798A
Synonyms: LY-3841136 sodium
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Cat. No.: HY-P11245
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Cat. No.: HY-P4863
CAS No.: 1678415-18-3
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Cat. No.: HY-P2285
CAS No.: 151804-79-4
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Cat. No.: HY-P88982A
Synonyms: AMY2; AMY3; HXA
Cat. No.: HY-10302R
CAS No.: 957116-20-0
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MK-3207 hydrochloride (Standard) is the analytical standard of MK-3207 hydrochloride (HY-10302). This product is intended for research and analytical applications. MK-3207 hydrochloride is a potent and orally bioavailable CGRP receptor antagonist with IC50 of 0.12 nM and Ki of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3.
Cat. No.: HY-RS00674
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AMY2B Human Pre-designed siRNA Set A contains three designed siRNAs for AMY2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-15498S
Synonyms: BMS-927711-d4; BHV-3000-d4
Cat. No.: HY-179728
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Amylin agonist 1 is an agonist of amylin receptor 3 (AMY3R), with an EC50 of 6.17 nM for stimulating cellular cAMP production. Amylin agonist 1 is also an agonist of calcitonin receptor (CTR), with an EC50 of 8.58 nM. Amylin agonist 1 can be used for the research of type 2 diabetes and obesity .
Cat. No.: HY-P11843
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
