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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Ala-Ser
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Ala-Ser" in MCE Product Catalog:
1
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Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid (ALA) and porphobilinogen (PBG) levels. Givosiran demonstrates potent inhibitory activity against ALAS1 in mouse, rat, and cynomolgus monkey models. Givosiran can be used for the research of acute hepatic porphyria (AHP) .
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1 Cited Publications
Synonyms: ALN-AS1 sodium
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Givosiran (ALN-AS1) sodium is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran sodium downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid (ALA) and porphobilinogen (PBG) levels. Givosiran sodium demonstrates potent inhibitory activity against ALAS1 in mouse, rat, and cynomolgus monkey models. Givosiran sodium can be used for the research of acute hepatic porphyria (AHP) .
Cat. No.: HY-B1880
CAS No.: 19666-30-9
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Oxadiazon is an orally active herbicide. Oxadiazon reduces hepatic cytochrome P450 levels. Oxadiazon increases palmitoyl CoA oxidase, acetyl carnitine transferase, and hepatic ALAS activity. Oxadiazon induces hepatomegaly and experimental porphyria. Oxadiazon controls weeds. Oxadiazon may be used in neurodegenerative disease research .
Cat. No.: HY-P1756
CAS No.: 17351-32-5
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Cat. No.: HY-B1880R
CAS No.: 19666-30-9
Research Areas:
Oxadiazon (Standard) is the analytical standard of Oxadiazon (HY-B1880). This product is intended for research and analytical applications. Oxadiazon is an orally active herbicide. Oxadiazon reduces hepatic cytochrome P450 levels. Oxadiazon increases palmitoyl CoA oxidase, acetyl carnitine transferase, and hepatic ALAS activity. Oxadiazon induces hepatomegaly and experimental porphyria. Oxadiazon controls weeds. Oxadiazon may be used in neurodegenerative disease research .
Cat. No.: HY-P2386
CAS No.: 252554-78-2
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Cat. No.: HY-P4022
CAS No.: 291297-58-0
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Cat. No.: HY-P4320
CAS No.: 166184-23-2
Cat. No.: HY-W009215
CAS No.: 17351-33-6
Synonyms: L-Met-L-Ala-L-Ser
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Cat. No.: HY-P5510
CAS No.: 188530-20-3
Synonyms: HCV NS3 protease substrate
Cat. No.: HY-RS00554
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ALAS1 Human Pre-designed siRNA Set A contains three designed siRNAs for ALAS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00555
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ALAS2 Human Pre-designed siRNA Set A contains three designed siRNAs for ALAS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17599
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Alas1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Alas1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19407
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Alas2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Alas2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24059
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Alas1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Alas1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P3420
CAS No.: 866128-65-6
Cat. No.: HY-RS25899
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Alas2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Alas2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-187112
CAS No.: 202739-37-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
