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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
Amfenac
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "Amfenac" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-17479A
CAS No.: 61618-27-7
Target:
Research Areas:
Amfenac Sodium Hydrate is a COX-2 inhibitor.
Cat. No.: HY-17357
CAS No.: 78281-72-8
Synonyms: AHR 9434; AL 6515
Target:
Research Areas:
Neurological Disease Inflammation/Immunology Endocrinology Cancer
Nepafenac (AHR 9434; AL 6515), a nonsteroidal anti-inflammatory agent, is a topically administered COX-2 inhibitor with an IC50 of 0.12 μM. Nepafenac exhibits only weak COX-1 inhibitory activity (IC50 = 64.3 μM). Nepafenac possesses unique prodrug properties, which enable it to rapidly convert into the active metabolite Amfenac (HY-17479) in the ocular tissues, thereby achieving high concentrations in the retina and choroid. Nepafenac reduces inflammation and pain by inhibiting the activity of cyclooxygenase (COX) enzymes and thereby decreasing the production of prostaglandin PGE₂. Nepafenac can delay the metastasis of uveal melanoma (UM) in rabbit eyes. Nepafenac is mainly used for pain management and inflammation control after ophthalmic surgeries .
Cat. No.: HY-17357S
CAS No.: 1246814-53-8
Synonyms: AHR-9434-d5; AL-6515-d5
Cat. No.: HY-17479BS
Cat. No.: HY-17479S
CAS No.: 2749329-56-2
Cat. No.: HY-17479AR
CAS No.: 61618-27-7
Target:
Research Areas:
Amfenac (Sodium Hydrate) (Standard) is the analytical standard of Amfenac (Sodium Hydrate). This product is intended for research and analytical applications. Amfenac Sodium Hydrate is a COX-2 inhibitor.
Cat. No.: HY-17479
CAS No.: 51579-82-9
Target:
Research Areas:
Amfenac (AHR 5850) is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac can be used for the research of acute and chronic inflammation .
Cat. No.: HY-17479B
CAS No.: 61941-56-8
Synonyms: AHR 5850 sodium
Target:
Research Areas:
Amfenac sodium (AHR 5850 sodium) is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac sodium can be used for the research of acute and chronic inflammation .
Cat. No.: HY-W010649R
CAS No.: 288-14-2
Target:
HSP Reference Standards Epigenetic Reader Domain ATP-binding cassette (ABC) transporters Bacterial Fungal Antibiotic
Research Areas:
Amfenac (Sodium Hydrate) (Standard) is the analytical standard of Amfenac (Sodium Hydrate). This product is intended for research and analytical applications. Amfenac Sodium Hydrate is a COX-2 inhibitor.
Cat. No.: HY-183918
CAS No.: 61941-57-9
Target:
Research Areas:
Amfenac ethyl ester is an orally active cyclooxygenase (COX) inhibitor. Amfenac ethyl ester exhibits antiinflammatory activity in rodent models. Amfenac ethyl ester can be used for the research of inflammation .
Cat. No.: HY-17357R
CAS No.: 78281-72-8
Synonyms: AHR 9434 (Standard); AL 6515 (Standard)
Research Areas:
Neurological Disease Inflammation/Immunology Endocrinology Cancer
Nepafenac (AHR 9434; AL 6515) (Standard) is the analytical standard of Nepafenac (HY-17357). This product is intended for research and analytical applications. Nepafenac, a nonsteroidal anti-inflammatory agent, is a topically administered COX-2 inhibitor with an IC50 of 0.12 μM. Nepafenac exhibits only weak COX-1 inhibitory activity (IC50 = 64.3 μM). Nepafenac possesses unique prodrug properties, which enable it to rapidly convert into the active metabolite Amfenac (HY-17479) in the ocular tissues, thereby achieving high concentrations in the retina and choroid. Nepafenac reduces inflammation and pain by inhibiting the activity of cyclooxygenase (COX) enzymes and thereby decreasing the production of prostaglandin PGE₂. Nepafenac can delay the metastasis of uveal melanoma (UM) in rabbit eyes. Nepafenac is mainly used for pain management and inflammation control after ophthalmic surgeries.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
