4 Results for "

Anhydroicaritin

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Anhydroicaritin" in MCE Product Catalog:

3
β-Anhydroicaritin
β-Anhydroicaritin
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3 Cited Publications
Cat. No.: HY-N1940
CAS No.: 38226-86-7
Synonyms: Cycloicaritin
Category:  

Flavonols Flavonoids Plants Burseraceae Disease Research Fields Inflammation/Immunology Boswellia carterii

Target:  

Interleukin Related TNF Receptor MMP

β-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties . β-Anhydroicaritin ameliorates the degradation of periodontal tissue and inhibits the synthesis and secretion of TNF-α and MMP-3 in diabetic rats . β-Anhydroicaritin decreases the overproduction of NO, IL-10, TNF-α, MCP-1 and IL-6 in inperitonitis mice. β-Anhydroicaritin inhibits the elevation of intracellular Ca 2+, and markedly decreases iNOS protein expression .
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11
Icaritin
Icaritin
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11 Cited Publications
Cat. No.: HY-N0678
CAS No.: 118525-40-9
Synonyms: Anhydroicaritin
Category:  

Flavonols Plants Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Phenols Polyphenols Epimedium brevicornu Maxim. Berberidaceae Disease Research Fields Cancer

Target:  

JAK Autophagy Apoptosis

Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 µM) and primary CML cells (IC50 of 13.4 µM for CML-CP and 18 µM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis [3.
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Icaritin (Standard)
Icaritin (Standard)
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Cat. No.: HY-N0678R
CAS No.: 118525-40-9
Synonyms: Anhydroicaritin (Standard)
Category:  

Flavonols Human Gut Microbiota Metabolites Flavonoids Phenols Polyphenols Epimedium brevicornu Maxim. Plants Berberidaceae Endogenous metabolite

Target:  

JAK Reference Standards Autophagy Apoptosis

Icaritin (Standard) is the analytical standard of Icaritin. This product is intended for research and analytical applications. Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 μM) and primary CML cells (IC50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis [3.
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Anhydroicaritin-3,7-di-O-glucuronide
Anhydroicaritin-3,7-di-O-glucuronide
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Cat. No.: HY-N19800
CAS No.: 1231899-06-1
Category:  

Flavonols Flavonoids Endogenous metabolite

Target:  

Drug Metabolite

Anhydroicaritin-3,7-di-O-glucuronide is a diglucuronide metabolite of icaritin. Anhydroicaritin-3,7-di-O-glucuronide is also a conjugated metabolite derived from prenylated flavonoids of the genus *Epimedium* in rats. In an in vitro microsomal system, Anhydroicaritin-3,7-di-O-glucuronide is mainly catalyzed by UGT1A1 and UGT1A8. Anhydroicaritin-3,7-di-O-glucuronide is generated via sequential glucuronidation at the 3-OH and 7-OH sites of icaritin, or via further conversion from monoglucuronides of icaritin .
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