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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Antianginal effects
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Antianginal effects" in MCE Product Catalog:
9
9 Publications Verification
Cat. No.: HY-16952A
CAS No.: 74764-40-2
Synonyms: (±)-Bepridil hydrochloride hydrate; Org 5730 hydrochloride hydrate
Target:
Research Areas:
Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca + channel antagonist and Na +, K + channel inhibitor, with antianginal and type I antiarrhythmic effects. Bepridil hydrochloride hydrate also acts as a cardiac Na +/Ca2 + exchange (NCX1) inhibitor. Bepridil hydrochloride hydrate can be used for the research of cardiovascular disorders .
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Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP) . Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor . Antianginal agent.
1
1 Cited Publications
Cat. No.: HY-B0683
CAS No.: 74397-12-9
Synonyms: 17α,20-dimethyl-δ2-PGE1; ONO1206; OP1206
Target:
Research Areas:
Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research .
Cat. No.: HY-B0280S1
CAS No.: 1092804-88-0
Cat. No.: HY-B0280S2
CAS No.: 1054624-77-9
Cat. No.: HY-B0280S
CAS No.: 1092804-87-9
Synonyms: CVT 303-d5; RS 43285-003-d5
Cat. No.: HY-19115
CAS No.: 153192-22-4
Target:
Research Areas:
YM-430 is an oral active calcium entry-blocking and beta-adrenoceptor-blocking agent. YM-430 inhibits Amifampridine (HY-14946)-induced rhythmic contractions with an IC50 value of 59.2 nM and inhibits arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg. YM-430 can be used for study of angina pectoris .
Cat. No.: HY-U00151
CAS No.: 79700-61-1
Target:
Research Areas:
Dopropidil is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity and
anti-ischemic effects in several predictive animal models.
Cat. No.: HY-U00151A
CAS No.: 117241-47-1
Target:
Research Areas:
Dopropidil hydrochloride is a novel anti-anginal calcium ion modulating agent, possessing intracellular calcium antagonist activity and
anti-ischemic effects in several predictive animal models.
Cat. No.: HY-B0280R
CAS No.: 95635-55-5
Synonyms: CVT 303 (Standard); RS 43285-003 (Standard)
Research Areas:
Ranolazine (Standard) is the analytical standard of Ranolazine. This product is intended for research and analytical applications. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP) . Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor . Antianginal agent.
Cat. No.: HY-B0683S
CAS No.: 1263190-37-9
Cat. No.: HY-186062
CAS No.: 2234283-04-4
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
HCN-IN-1 is a TLR4 inhibitor and HCN channel modulator with activity against HCN2 and HCN4.HCN-IN-1 inhibits TLR4-mediated alkaline phosphatase (SEAP) signal activity.HCN-IN-1 reduces HCN2 current across tested voltages, shifts voltage-dependent activation to more hyperpolarized potentials, slows activation kinetics, and does not affect deactivation process.HCN-IN-1 blocks HCN4 current.HCN-IN-1 exhibits analgesic, anti-inflammatory, and anti-anginal effects.HCN-IN-1 can be used for the research of inflammatory pain, neuropathic pain, heart failure, inflammation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
