1 Result for "

Anticancer agent 358

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Anticancer agent 358" in MCE Product Catalog:

Cat. No.: HY-187679
CAS No.: 3087062-38-9
Target:  

PARP Apoptosis Autophagy

Research Areas:  

Cancer

Anticancer agent 358 is a PARP inhibitor with antiproliferative activity against lung cancer cells and low toxicity to normal hepatocytes. Anticancer agent 358 binds to the active site of PARP via hydrogen bonds and π-π interactions with key residues, thereby promoting the accumulation of DNA damage. Anticancer agent 358 induces DNA damage, apoptosis, and autophagy in lung cancer cells. Anticancer agent 358 can be used for the research of non-small cell lung cancer .
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