7 Results for "

Atrogin-1

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Atrogin-1" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-N0597
CAS No.: 32791-84-7
Panaxatriol is an orally active dammarane-type tetracyclic triterpene sapogenin. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer [1][2][3].
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1
1 Cited Publications
Cat. No.: HY-P81082
Synonyms: Fbx32; 4833442G10Rik; AI430017; Atrogin 1; Atrogin-1; Atrogin1; Atrophy gene 1; F box only protein 32; F-box only protein 32; F-box protein 32; FBX32_HUMAN; fbxo25; FBXO32; FLJ32424; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F box; Muscle atrophy F box protein; Muscle atrophy F-box protein.

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-N0597R
CAS No.: 32791-84-7
Panaxatriol (Standard) is the analytical standard of Panaxatriol. This product is intended for research and analytical applications. Panaxatriol is an orally active dammarane-type tetracyclic triterpene sapogenin. Panaxatriol enhances the phosphorylation levels of Akt, insulin receptor and p70S6K in skeletal muscle. Panaxatriol reduces the mRNA expression level of Atrogin1 in skeletal muscle. Panaxatriol induces apoptosis, pre-G1 cell cycle arrest and increased intracellular ROS levels in prostate cancer cells, decreases mitochondrial membrane potential, inhibits cell migration and reduces colony formation. Panaxatriol can be used in research related to insulin resistance, myocardial ischemia/reperfusion injury and prostate cancer [1] .
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Cat. No.: HY-RS26660
Research Areas:  

Others

Fbxo32 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fbxo32 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-182062
CAS No.: 931366-46-0
Target:  

NAMPT E1/E2/E3 Enzyme

Research Areas:  

Neurological Disease

NAMPT activator-9 (Compound DIPM) is an allosteric, non-competitive NAMPT activator, with an EC50 of 3.366 μM against hNAMPT. NAMPT activator-9 enhances the enzymatic activity of NAMPT via an allosteric, non-competitive mechanism. NAMPT activator-9 increases intracellular NAD + levels. NAMPT activator-9 restores myotube diameter and reduces the expression of atrophy markers Atrogin-1 and MuRF1. NAMPT activator-9 is applicable to research related to muscle atrophy [1].
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Cat. No.: HY-N12489
CAS No.: 2263882-48-8
Ishophloroglucin A is an orally active phlorotannin compound found in Ishige okamurae. Ishophloroglucin A can alleviate Dexamethasone (HY-14648)-induced muscle atrophy through muscle protein metabolism. Ishophloroglucin A can improve impaired protein synthesis (PI3K and Akt) or degradation (muscle-specific ubiquitin ligase muscle RING finger and atrogin-1). Ishophloroglucin A can be used for research of muscle atrophy-related diseases [1].
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Cat. No.: HY-RS20156
Research Areas:  

Others

Fbxo32 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fbxo32 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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