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Cat. No.: HY-N12489

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Ishophloroglucin A

Ishophloroglucin A is an orally active phlorotannin compound found in Ishige okamurae. Ishophloroglucin A can alleviate Dexamethasone (HY-14648)-induced muscle atrophy through muscle protein metabolism. Ishophloroglucin A can improve impaired protein synthesis (PI3K and Akt) or degradation (muscle-specific ubiquitin ligase muscle RING finger and atrogin-1). Ishophloroglucin A can be used for research of muscle atrophy-related diseases.

For research use only. We do not sell to patients.

CAS No.: 2263882-48-8
Formula: C₉₆H₆₆O₄₈
Molecular Weight:1987.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Ishophloroglucin A Chemical Structure

CAS No.: 2263882-48-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All PI3K Isoforms :

All Akt Isoforms :

Chemical Information

CAS No. 2263882-48-8
Molecular Weight 1987.52
Formula C₉₆H₆₆O₄₈
SMILES

OC1=CC(O)=C(OC2=CC(O)=C(C(O)=C2)OC3=CC(O)=C(C(O)=C3)OC4=CC(O)=C(C(O)=C4)OC5=CC(O)=C(C(O)=C5)OC6=CC(O)=C(C(O)=C6)OC7=CC(O)=C(C(O)=C7)OC8=C(OC9=C(C=C(C=C9O)OC%10=C(OC%11=C(OC%12=C(OC%13=C(C=C(C=C%13O)OC%14=C(OC%15=C(C=C(C=C%15O)OC%16=CC(O)=CC(O)=C%16)O)C(O)=CC(O)=C%14)O)C=C(O)C=C%12O)C=C(O)C=C%11O)C=C(O)C=C%10O)O)C(O)=CC(O)=C8)C(O)=C1
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Marine natural products
- Marine algae
Ishige okamurae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yang HW, et al. Ishophloroglucin A, Isolated from Ishige okamurae, Alleviates Dexamethasone-Induced Muscle Atrophy through Muscle Protein Metabolism In Vivo. Mar Drugs. 2022 Apr 22;20(5):280. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Ishophloroglucin A

All PI3K Isoforms

All Akt Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Ishophloroglucin A Related Classifications

HY-N12489 Related Classifications